Impacto epidemiológico y económico de la vacunación contra el tétanos en adultos de Colombia

Alvis, Nelson; Hoz, Fernando de la; Gamboa, Óscar; Cediel, Natalia; Rico, Alejandro; Paternina, Angel; Alvis, Luis

doi:10.1590/s1020-49892011000900004

Cited by 7 publications

(6 citation statements)

References 13 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These prices are near the ones considered in the base case analysis of this study. A reduced price would be also consistent with prices of other vaccines in Colombia, like pneumococcal and tetanus vaccines, which are deemed ‘very cost-effective’ at prices per dose between USD1.4 and US$ 14 [ 49 , 50 ].…”

Section: Discussionmentioning

confidence: 86%

See 1 more Smart Citation

Cost-Effectiveness Analysis of the Bivalent and Quadrivalent Human Papillomavirus Vaccines from a Societal Perspective in Colombia

et al. 2013

Self Cite

View full text Add to dashboard Cite

ObjectiveTo compare costs and effectiveness of three strategies used against cervical cancer (CC) and genital warts: (i) Screening for CC; (ii) Bivalent Human Papillomavirus (HPV) 16/18 vaccine added to screening; (iii) Quadrivalent HPV 6/11/16/18 vaccine added to screening. MethodsA Markov model was designed in order to simulate the natural history of the disease from 12 years of age (vaccination) until death. Transition probabilities were selected or adjusted to match the HPV infection profile in Colombia. A systematic review was undertaken in order to derive efficacy values for the two vaccines as well as for the operational characteristics of the cytology test. The societal perspective was used. Effectiveness was measured in number of averted Disability Adjusted Life Years (DALYS). ResultsAt commercial prices reported for 2010 the two vaccines were shown to be non-cost-effective alternatives when compared with the existing screening strategy. Sensitivity analyses showed that results are affected by the cost of vaccines and their efficacy values, making it difficult to determine with certainty which of the two vaccines has the best cost-effectiveness profile. To be ‘cost-effective’ vaccines should cost between 141 and 147 USD (Unite States Dollars) per vaccinated girl at the most. But at lower prices such as those recommended by WHO or the price of other vaccines in Colombia, HPV vaccination could be considered very cost-effective.ConclusionsHPV vaccination could be a convenient alternative for the prevention of CC in Colombia. However, the price of the vaccine should be lower for this vaccination strategy to be cost-effective. It is also important to take into consideration the willingness to pay, budgetary impact, and program implications, in order to determine the relevance of a vaccination program in this country, as well as which vaccine should be selected for use in the program.

show abstract

Section: Discussionmentioning

confidence: 86%

“…As far as vaccination in Colombia is concerned, other strategies classified as ‘very cost-effective’, with an ICER lower than the per capita GDP, have been found recently. Such is the case of the conjugated pneumococcal vaccine [ 48 ],the tetanus vaccine[ 49 ] and the Pneumovax 23 in adults over 28 years of age [ 50 ].…”

Section: Discussionmentioning

confidence: 99%

Cost-Effectiveness Analysis of the Bivalent and Quadrivalent Human Papillomavirus Vaccines from a Societal Perspective in Colombia

et al. 2013

Self Cite

View full text Add to dashboard Cite

show abstract

“…Health equity issues related to sex [146, 197–204], high-risk groups (e.g. commercial sex workers) [205–207] or marginalised groups (e.g.…”

Section: Resultsmentioning

confidence: 99%

Operations research in global health: a scoping review with a focus on the themes of health equity and impact

Bradley

Jung

Tandon-Verma

et al. 2017

Health Res Policy Sys

View full text Add to dashboard Cite

BackgroundOperations research (OR) is a discipline that uses advanced analytical methods (e.g. simulation, optimisation, decision analysis) to better understand complex systems and aid in decision-making.SummaryHerein, we present a scoping review of the use of OR to analyse issues in global health, with an emphasis on health equity and research impact. A systematic search of five databases was designed to identify relevant published literature. A global overview of 1099 studies highlights the geographic distribution of OR and common OR methods used. From this collection of literature, a narrative description of the use of OR across four main application areas of global health – health systems and operations, clinical medicine, public health and health innovation – is also presented. The theme of health equity is then explored in detail through a subset of 44 studies. Health equity is a critical element of global health that cuts across all four application areas, and is an issue particularly amenable to analysis through OR. Finally, we present seven select cases of OR analyses that have been implemented or have influenced decision-making in global health policy or practice. Based on these cases, we identify three key drivers for success in bridging the gap between OR and global health policy, namely international collaboration with stakeholders, use of contextually appropriate data, and varied communication outlets for research findings. Such cases, however, represent a very small proportion of the literature found.ConclusionPoor availability of representative and quality data, and a lack of collaboration between those who develop OR models and stakeholders in the contexts where OR analyses are intended to serve, were found to be common challenges for effective OR modelling in global health.Electronic supplementary materialThe online version of this article (doi:10.1186/s12961-017-0187-7) contains supplementary material, which is available to authorized users.

show abstract

“…(6) Explanation to this fact is related to two main aspects: one is that men are more exposed due to their professions. Many tetanus cases occurs in those working with soil such as agricultures, gardeners and bricklayers.…”

Section: Discussionmentioning

confidence: 99%

Tetanus – An Evaluation of Epidemiologic Data in Brazil

Dias¹,

Ferrer²,

Guerreiro³

2014

BJMHH

View full text Add to dashboard Cite

Tetanus is an infectious preventable disease caused by Clostridium tetani that still occurs in large numbers in Brazil and has high mortality rates. Epidemiological data on morbidity and mortality of accidental and neonatal tetanus in Brazil from 2008 to 2011 were collected from the System of Information of Notifiable Diseases available on line. There were 1299 cases of accidental tetanus cases with 419 (32%) deaths. Men aged 20 to 59 years were most affected. High numbers of accidental tetanus are probably related to more exposure to risk factors. The lack of special campaigns for tetanus revaccinations every ten years is another important factor. The fewer number of cases of neonatal tetanus (23) is related to the success of governmental vaccination program targeted to this age group. Despite low numbers, death rate is high, 65% among neonatal cases.

show abstract

Impacto epidemiológico y económico de la vacunación contra el tétanos en adultos de Colombia

Cited by 7 publications

References 13 publications

Cost-Effectiveness Analysis of the Bivalent and Quadrivalent Human Papillomavirus Vaccines from a Societal Perspective in Colombia

Cost-Effectiveness Analysis of the Bivalent and Quadrivalent Human Papillomavirus Vaccines from a Societal Perspective in Colombia

Operations research in global health: a scoping review with a focus on the themes of health equity and impact

Tetanus – An Evaluation of Epidemiologic Data in Brazil

Contact Info

Product

Resources

About