Impacto del cribado y tratamiento del bajo flujo sistémico en la prevención de hemorragia intraventricular grave y/o muerte en el prematuro

Oulego-Erróz, Ignacio; Quintela, Paula Alonso; González, Aquilina Jiménez; Seara, S.; Blanco, S. Rodríguez; Varas, María Rosón; López, Leticia Castañón

doi:10.1016/j.anpedi.2018.02.010

Cited by 4 publications

References 43 publications

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NT-PROBNP as a screening tool for low-risk patent ductus arteriousus: a follow-up validation study

López-Blanco,

Oulego-Erroz,

Pou-Blázquez

et al. 2023

Eur J Pediatr

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Purpose: To test whether NT-proBNP serves as a screening for low-risk patent ductus arteriosus and safely avoids routine early echocardiography.Methods: Prospective observational study in preterm infants below 33 weeks of gestational age. Infants with >5100 pg/ml (positive screening) at 48-72 hours of life received comprehensive echocardiography and were treated according to shunt severity. Infants with NT-proBNP below 5100 pg/ml (negative screening) were managed expectantly. The main outcome was need for ductus treatment within the rst 7 days of life.Result: 125 infants were included; 82 had a negative and positive NT-proBNP screening respectively. No infant (0%) with a negative screening was treated for ductus while 26 (60.4%) with a positive screening were treated (p<0.001). NT-proBNP avoided a 65.6% of routine echocardiograms. NT-proBNP had an excellent performance to predict treatment (AUC=0.967) Conclusions: NT-proBNP at 48-72 hours of life has an excellent performance to detect low-risk and avoids unnecessary echocardiograms. This may contribute to optimize PDA management in terms of resource utilization.

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NT-PROBNP as a screening tool for low-risk patent ductus arteriousus: a follow-up validation study

López-Blanco,

Oulego-Erroz,

Pou-Blázquez

et al. 2023

Eur J Pediatr

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Association between early echocardiography screening of low systemic blood flow and intraventricular hemorrhage in preterm infants: a multicenter cohort study

Terroba-Seara,

Oulego-Erroz,

Palanca-Arias

et al. 2024

J Perinatol

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Nt-probnp as a Screening for Low-risk Patent Ductus Arteriousus: a Follow-up Validation Study

López-Blanco,

Oulego-Erroz,

Pou-Blázquez

et al. 2023

Preprint

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Purpose: To test whether NT-proBNP serves as a screening for low-risk patent ductus arteriosus and safely avoids routine early echocardiography. Methods: Prospective observational study in preterm infants below 33 weeks of gestational age. Infants with >5100 pg/ml (positive screening) at 48-72 hours of life received comprehensive echocardiography and were treated according to shunt severity. Infants with NT-proBNP below 5100 pg/ml (negative screening) were managed expectantly. The main outcome was need for ductus treatment within the first 7 days of life. Result: 125 infants were included; 82 had a negative and positive NT-proBNP screening respectively. No infant (0%) with a negative screening was treated for ductus while 26 (60.4%) with a positive screening were treated (p<0.001). NT-proBNP avoided a 65.6% of routine echocardiograms. NT-proBNP had an excellent performance to predict treatment (AUC=0.967) Conclusions: NT-proBNP at 48-72 hours of life has an excellent performance to detect low-risk and avoids unnecessary echocardiograms. This may contribute to optimize PDA management in terms of resource utilization.

show abstract

Impacto del cribado y tratamiento del bajo flujo sistémico en la prevención de hemorragia intraventricular grave y/o muerte en el prematuro

Cited by 4 publications

References 43 publications

NT-PROBNP as a screening tool for low-risk patent ductus arteriousus: a follow-up validation study

NT-PROBNP as a screening tool for low-risk patent ductus arteriousus: a follow-up validation study

Association between early echocardiography screening of low systemic blood flow and intraventricular hemorrhage in preterm infants: a multicenter cohort study

Nt-probnp as a Screening for Low-risk Patent Ductus Arteriousus: a Follow-up Validation Study

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