Impact of vitamin C level on osteoporosis of postmenopausal Iraqi women

Abstract

A common disease, Osteoporosis (OP), is characterized by a systemic impairment of microarchitecture and bone mass that causes in fragility fractures. The medical and socioeconomic influences of postmenopausal OP will increase, meanwhile, oxidative Stress (OS) and inflammation are play an important role in this disease. The intracellular antioxidant vitamin (C ;VitC) is important for a variety of biological functions, and prevents of inflammation and OS. The purpose of this study is investigation the impact Vit C in this silent disease. Total of (150) individual samples were included ; 50 individual for each group (apparently healthy individual samples as control group, Osteopenia patients , and OP patients ). These three groups were classified according to the T-Score obtained from the DEXA scan. The vitamin was measured by ELISA immunological method while several biochemical parameters including calcium (Ca++), phosphorus (Phos), total protein (TP), and uric acid (UA) were measured using autobiochemical analysis. Results showed significantly decrease in Vit C in two patients groups when compared with control group but the difference was non-significant between the two patient groups.