Impact of Ureteral Stent Material on Stent-related Symptoms: A Systematic Review of the Literature

Boeykens, Matthias; Keller, Etienne Xavier; Bosio, Andrea; Wiseman, Oliver; Contreras, P; Ventimiglia, Eugenio; Talso, Michele; Pietropaolo, Amelia; Tailly, Thomas; Coninck, Vincent De

doi:10.1016/j.euros.2022.09.005

Cited by 11 publications

(8 citation statements)

References 48 publications

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“…В систематическом обзоре M. Boeykens et al (2022) отмечено, что пациентки, кото-рым был установлен внутренний мочеточниковый стент, в 88% случаев испытывали тот или иной дискомфорт, связанный с инородным телом в мочевых путях [7]. Возникновение «стент-зависимых симптомов» связано с пузырно-лоханочным рефлюксом, формой и длиной дистального завитка.…”

Section: Discussionunclassified

Efficacy of combined phytotherapy (NefroBest® and UroBest®) in female patients with urolithiasis and preoperative drainage of upper urinary tract before ureteroscopy

Kotov,

Nemenov,

Perov

2024

Vestn. Urol.

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Introduction. In most cases, double-J stent placement is the initial method of drainage in patients with urolithiasis. Until ureteroscopic intervention, most patients report «stent-related symptoms» that reduce the quality of life.Objective. To improve the results of treatment in female patients with urinary stone disease (USD) and preoperative drainage of the upper urinary tract using double-J stent by assessing the effect of the NefroBest® and UroBest® complexes on the prevention of the development of «stent-related symptoms» and inflammatory processes.Materials & methods. The study group included 90 female patients with USD, who were performed ureteroscopic interventions with preoperative stent placement from March to September 2023 in the Yudin City Clinical Hospital. Patients were divided into two groups: the main group 1 (n = 30) — patients who received phytotherapy with NefroBest® (30 days) and UroBest® (7 days) complexes after placement of an internal ureteral stent; the control group 2 (n = 60) — patients who did not receive specific therapy postoperatively.Results. According to the USSQ, in group 1 the median score due to urinary symptoms was 22 points, and in group 2 — 28 points (p = 0.001), when assessing symptoms associated with pain — 12 and 18 points (p < 0.001), general health — 17 points both and work performance — 9 and 11 points, respectively. Among patients in group 1, stonefree rate was observed in 90.0%, and among patients in group 2 — in 93.3%. In group 1, antibacterial therapy in the postoperative period was in 37.0% of patients, and in group 2 – among 53.0%.Conclusion. The co-use of the NefroBest® and UroBest® complexes in female patients with USD and preoperative drainage of the upper urinary tract using double-J stent can reduce the severity of symptoms associated with urination and pain, and postoperatively resulted in a lower incidence of infectious-inflammatory complications.

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Section: Discussionunclassified

Efficacy of combined phytotherapy (NefroBest® and UroBest®) in female patients with urolithiasis and preoperative drainage of upper urinary tract before ureteroscopy

Kotov,

Nemenov,

Perov

2024

Vestn. Urol.

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“…The incidence of stent-related symptoms is influenced by the stent composition. Soft ureteral stents might reduce SRS when compared to hard ones, even if the quality of evidence is low [ 5 ]. SRS are also determined by the encrustation rate and the bacterial adhesion incidence [ 5 ].…”

Section: Methodsmentioning

confidence: 99%

“…Hydrogel coated stents are highly biocompatible and have a low coefficient of friction; with the addition of an antimicrobial, they may reduce bacterial growth [ 5 , 27 ]. Hydrophilic gel alone, however, does not reduce bacterial adhesion [ 28 ].…”

Section: Methodsmentioning

confidence: 99%

Comprehensive overview of ureteral stents based on clinical aspects, material and design

2023

Cent european J Urol

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Ureteral stents are useful devices in urological surgery. The main objective of a ureteric stent is to allow passage of urine and reduce early or late complications related to obstruction in the urinary tract. Despite their widespread use, there is a general lack of knowledge and awareness in stent composition and indication of application. We represented a synthesis of our extensive research over materials, coatings and shapes available on the market and then analyzed the main characteristics and peculiarities of ureteral stents. We have also focused our attention over the side effects and complication that must be considered when placing a ureteral stent. Encrustation, microbial colonization, stent-related symptoms and patient’s history must always be evaluated when there is the need for a ureteral stent. The perfect stent should have many characteristics including easy insertion and removal, easy manipulation, resistance to encrustation and migration, lack of complications, biocompatibility, radio-opacity, biodurability, affordability (cost-effectiveness), tolerability and optimal flow characteristics. Nevertheless, further research and studies need to be done to provide more information about stent composition and efficacy in vivo. In this narrative review, we covered the basic information and main characteristics of ureteral stents, in order to help clinicians choose the appropriate device needed for a given situation.

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“…In urological care, ureteral stents are widely used for various clinical applications, such as alleviating ureteric obstructions, aiding post-surgical drainage, and serving as a supplementary tool in endourological procedures [ 1 ]. However, they are often linked with a series of adverse stent-related symptoms (SRS), including but not limited to painful urination, elevated urinary frequency, and abdominal discomfort [ 2 , 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…There have been advances in ureteral stent design, which include antireflux membrane valves, polymeric flap valves, and many others. These stents aim to reduce SRS by minimizing vesicoureteral reflux, which is commonly observed with conventional stents [ 1 ]. The antireflux membrane valve, highlighted by Ecke et al [ 5 , 6 ], is clinically accessible and employs a silicone membrane situated at the vesical end of the double J stent (JJ stent/DJS), forming a one-way valve, thereby obstructing intraluminal vesicoureteral reflux (VUR) upon escalation of bladder pressure.…”

Section: Introductionmentioning

confidence: 99%

Antireflux Ureteral Stents Prevent Stent-Related Symptoms: A Meta-Analysis of Randomized Controlled Trials

Adhoni,

Al Homsi,

Ali

et al. 2023

Cureus

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Ureteral stents are widely used in urological care, but they are often associated with adverse stent-related symptoms (SRS), such as painful urination, elevated urinary frequency, and abdominal discomfort. Antireflux ureteral stents have been developed to reduce stent-related pain and reflux by minimizing vesicoureteral reflux (VUR). This systematic review and meta-analysis of randomized controlled trials (RCTs) was undertaken to assess the efficacy of antireflux ureteral stents in mitigating SRS compared to conventional urethral stents. Our study included a total of 269 cases from three RCTs. The meta-analysis showed that antireflux ureteral stents were significantly more effective than standard stents in reducing SRS, including stent-related pain (odds ratio (OR): 4.80, 95% CI: 2.77, 8.31, p <0.00001), severe stent-related pain (OR: 8.35, 95% CI: 2.12, 32.89, p=0.002), flank pain while urinating (OR: 5.98, 95% CI: 3.35, 10.68, p <0.00001), and severe flank pain while urinating (OR: 15.79, 95% CI: 2.91, 85.57, p=0.001). There was no significant difference in the rates of postoperative creatinine abnormality or postoperative hydronephrosis between the two groups. Therefore, antireflux ureteral stents are more effective than standard stents in reducing SRS. This suggests that antireflux ureteral stents should be considered for patients undergoing ureteral stenting.

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Impact of Ureteral Stent Material on Stent-related Symptoms: A Systematic Review of the Literature

Cited by 11 publications

References 48 publications

Efficacy of combined phytotherapy (NefroBest® and UroBest®) in female patients with urolithiasis and preoperative drainage of upper urinary tract before ureteroscopy

Efficacy of combined phytotherapy (NefroBest® and UroBest®) in female patients with urolithiasis and preoperative drainage of upper urinary tract before ureteroscopy

Comprehensive overview of ureteral stents based on clinical aspects, material and design

Antireflux Ureteral Stents Prevent Stent-Related Symptoms: A Meta-Analysis of Randomized Controlled Trials

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