Abstract:1 4 DISCLOSURE The authors declare no conflicts of interest. 3 / 1 4 Purpose: To evaluate the impact of ultrasonography (US) on identifying noninvasive prenatal screening (NIPS) false-negative aneuploidy. Methods: Analysis of large population-based NIPS false-negative aneuploidy data comprising karyotypes, clinical outcomes, and US results.Results: From December 2010 to July 2018, a total of 3,320,457 pregnancies were screened by NIPS performed in BGI; among them, 69 NIPS false-negative aneuploidy cases with i… Show more
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