Impact of treatment on quality of life for oral and oropharyngeal carcinoma

Infante-Cossio, Pedro; Torres-Carranza, E.; Cayuela, Aurelio; Hens-Aumente, Elena; Pastor-Gaitán, P.; Gutiérrez-Pérez, J.L.

doi:10.1016/j.ijom.2009.06.008

Cited by 58 publications

(59 citation statements)

References 22 publications

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“…There are specific instruments for head and neck cancer patients HRQoL evaluation such as: the EORTC QLQ-H&N35, the FACT H&N, the FLIC, the University of Washington Quality of Life Questionnaire (UW-QOL), the University of Michigan Head and Neck Quality of Life Questionnaire (HNQOL), the Head and Neck Radiotherapy Questionnaire (HNRQ), the Performance Status Scale-Head and Neck-(PSS-H&N), the Obturator Functioning Scale (OFS), the Late Side Effects on Daily Life Scale and the Oral and Pharyngeal Nursing Care Questionnaire (OPNCQ) [17-23]. …”

Section: Introductionmentioning

confidence: 99%

Patient reported outcomes in head and neck cancer: selecting instruments for quality of life integration in clinical protocols

et al. 2010

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BackgroundHealth Related Quality of Life has been used in medical research for more than twenty years, being progressively accepted during the last decade as an important patient reported outcome. Considering the multidimensional approach involved in Health Related Quality of Life assessment, instrument applicability and cultural adaptation must be tested for each population. In order to select the most appropriate instrument for Head and Neck cancer patients, two major Health Related Quality of Life specific questionnaires for Head and Neck cancer patients were compared. Conceptual differences, psychometric characteristics, scores, reliability, construct validity and sensitivity to symptomatology, tumour location, tumour size were analyzed.Methods102 consecutive Head and Neck cancer patients completed two different Health Related Quality of Life questionnaires: EORTC QLQ-C30 and its specific head and neck module QLQ-H&N35 and the Functional Assessment of Cancer Therapy Scales (FACT-H&N). Patients completed the questionnaires, immediately before consultation as a part of the routine evaluation.ResultsA greater variability was always found in the EORTC QLC-C30 questionnaire's scores for all comparable domains. Both instruments revealed a good internal consistency and demonstrated to be good tools to distinguish symptomatic patients. The EORTC questionnaires still demonstrated sensitivity to distinguish T3 and T4 staging. Conceptual differences and the psychometric characteristics are discussed. Our results suggest that these two instruments assess different aspects of Health Related Quality of Life - the questionnaires should be used separately and chosen according to the study objectives and methodology.ConclusionsThis study emphases the importance in selecting the appropriate tool as a critical success factor in implementing routine Health Related Quality of Life assessment in clinical practice. This decision assumes particularly importance when utilization of results in real time and integration into clinical protocols are considered.

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Section: Introductionmentioning

confidence: 99%

Patient reported outcomes in head and neck cancer: selecting instruments for quality of life integration in clinical protocols

et al. 2010

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“…Currently, the most commonly used method worldwide for oropharyngeal reconstruction is the radial forearm free flap followed by the anterolateral thigh flap (31). However, this microsurgical procedure is often slow and technique-sensitive (13). In addition, not all patients are suitable for a free flap reconstruction, particularly patients that are elderly and show poor general condition (29).…”

Section: Discussionmentioning

confidence: 99%

“…Traditionally, the oropharynx is one of the most challenging regions of the body to reconstruct and rehabilitate following cancer surgery due to the implications for speech, swallowing and respiratory function, which may eventually negatively affect the quality of life of patients (11)(12)(13). Various types of loco-regional and free flaps are used for oropharyngeal reconstruction; but, at present, this issue remains the subject of debate since no 'ideal method' for all situations exists (11,14).…”

Section: Introductionmentioning

confidence: 99%

Infrahyoid flap in oropharyngeal reconstruction following carcinoma resection: A study of 6 patients and literature review

et al. 2016

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Abstract. The present study aimed to describe the techniques used and the results obtained with the infrahyoid flap for the reconstruction of medium-sized oropharyngeal defects following resection for advanced squamous cell cancer. During a period of 1 year, six patients with oropharyngeal defects were reconstructed using the infrahyoid flap. The tumor characteristics, location and size of the defect, resective and reconstructive techniques employed and the complications and outcomes of the speech and swallowing functions, as identified in the follow-up visits every 3 months, were evaluated. All flaps were performed simultaneously in association with tumoral excision and ipsilateral supraomohyoid neck dissection. The mean size of the skin paddle was 7.0x3.5 cm. The donor site was primarily sutured. The postoperative course was uneventful and all flaps were viable. One case of marginal skin paddle loss occurred without affecting the survival of the flap. Five patients received postoperative radiotherapy and one patient received concurrent postoperative chemotherapy. During the follow-up period (mean, 63 months), all patients showed excellent oral swallowing. Speech was excellent in five patients and in one patient speech was classified as good. The aesthetic results of the cervical donor site were good. Based on the present case report and the literature review, the infrahyoid flap is a simple and safe procedure for the reconstruction of the oropharynx, with a high success rate, minimal donor site morbidity and good aesthetic and functional results. The infrahyoid flap is a valid surgical option that may be considered in selected oncological patients undergoing reconstruction of medium-size oropharyngeal defects.

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“…stádiumú daganatos betegek globális életminőség-érté-keinek változása alapján állapítottuk meg a daganatos betegek kezelést követő életminőségsúlyait [22]. Az I-II.…”

Section: Az Egyes Egészségi áLlapotokhoz Tartozó éLetminőség-súlyszámokunclassified

A szájüregi szűrés költséghatékonysága Magyarországon

2016

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Bevezetés: A szájüregi daganatok jelentős betegségterhet jelentenek Magyarországon. Célkitűzés: A szájüregi daganatok potenciális szűrési programjainak magyarországi költséghatékonyságát vizsgálták. Módszer: A 40 éves férfiak kö-rében háziorvosok által éves gyakorisággal végzett szervezett szűrés, illetve a 40 éves férfiak körében az alapellátás által végzett, kockázati csoportokat célzó alkalmi szűrés költséghatékonyságát hasonlították a "Nincs szűrés stratégi-ához". Az egyes egészségi állapotokhoz tartozó magyarországi hasznossági értékeket és egészségügyi költségeket, valamint a szűrőprogramok költségét a vizsgálat keretében becsülték. A kutatás főbb eredményei az egyes vizsgált stratégiák összes egészségügyi költsége, a várható életminőséggel korrigált életévek, valamint az inkrementális költ-séghatékonysági hányadosok. Eredmények: A rákmegelőző állapotok kezelésének hatásossága és a részvételi arány függvényében a vizsgált szűrési stratégiák 15-20 éves időtávon költséghatékonyak. A magas kockázatúakra irányuló alkalmi szűrés költséghatékonyabb, mint más vizsgált stratégiák. Következtetések: Magyarországon a magas kockáza-túakra irányuló alkalmi szájüregi szűrés költséghatékony lenne. A rákmegelőző állapotok terápiáinak hatásosságára vonatkozó modellparaméterek azonban igen bizonytalanok, az egészségpolitikai döntések előkészítéséhez további kutatások szükségesek. Orv. Hetil., 2016, 157(29), 1161-1170. Kulcsszavak: szájüregi daganatok, daganatos betegségek korai felfedezése, költséghatékonysági vizsgálat Cost-effectiveness of oral cancer screening in HungaryIntroduction: The burden of oral cancer is high in Hungary. Aim: To study the cost-effectiveness of potential oral cancer screening in Hungary. Method: Three strategies were compared: no introduction of screening, organized yearly screening for 40-year-old males in general medical practise, and opportunistic screening of high risk 40-yearold males in primary care. Local estimates of health utilities and costs of each health state and of the screening programmes were identified. The main outcomes were total costs, quality adjusted life years, and incremental cost-effectiveness ratios. Results: Depending on the efficacy of the treatments of precancerous lesions and the participation rate, screening strategies are cost-effective over a 15-20 year time course. The opportunistic screening of high risk people is more cost-effective than the other strategies. Conclusions: Opportunistic screening of high risk people would be cost-effective in Hungary. The uncertainty about the efficacy of the treatments of precancerous lesions requires more research to support evidence based health policy making.

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Impact of treatment on quality of life for oral and oropharyngeal carcinoma

Cited by 58 publications

References 22 publications

Patient reported outcomes in head and neck cancer: selecting instruments for quality of life integration in clinical protocols

Patient reported outcomes in head and neck cancer: selecting instruments for quality of life integration in clinical protocols

Infrahyoid flap in oropharyngeal reconstruction following carcinoma resection: A study of 6 patients and literature review

A szájüregi szűrés költséghatékonysága Magyarországon

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