Impact of Transient and Persistent Donor-Specific Antibodies in Lung Transplantation
S. Auner,
C. Hillebrand,
P. M. Boehm
et al.
Abstract:Lung transplantation (LuTx) is an established treatment for patients with end-stage lung diseases, however, outcomes are limited by acute and chronic rejection. One aspect that has received increasing attention is the role of the host’s humoral alloresponse, particularly the formation of de novo donor-specific antibodies (dnDSAs). The aim of this study was to investigate the clinical significance of transient and persistent dnDSAs and to understand their impact on outcomes after LuTx. A retrospective analysis … Show more
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