Impact of trans fatty acids of ruminant origin compared with those from partially hydrogenated vegetable oils on CHD risk

Pfeuffer, Maria; Schrezenmeir, Jürgen

doi:10.1016/j.idairyj.2006.06.016

Cited by 37 publications

(14 citation statements)

References 54 publications

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“…According to several authors, currently there is no convincing evidence to substantiate an association between current R-TFA intake and increased risk of coronary heart diseases (Nishida and Uauy 2009;Pfeuffer and Schrezenmeir 2006).…”

Section: Epidemiological and Clinical Studies Concerning R-tfa Or Indmentioning

confidence: 99%

Evaluation of the Impact of RuminantTransFatty Acids on Human Health: Important Aspects to Consider

Kuhnt

Degen

Jahreis

2015

Critical Reviews in Food Science and Nutrition

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The definition and evaluation of trans fatty acids (TFA) with regard to foodstuffs and health hazard are not consistent. Based on the current situation, the term should be restricted only to TFA with isolated double bonds in trans-configuration. Conjugated linoleic acids (CLA) should be separately assessed. Ideally, the origin of the consumed fat should be declared, i.e., ruminant TFA (R-TFA) and industrial TFA (non-ruminant; I-TFA). In ruminant fat, more than 50% of R-TFA consists of vaccenic acid (C18:1 t11). In addition, natural CLA, i.e., c9,t11 CLA is also present. Both are elevated in products from organic farming. In contrast to elaidic acid (t9) and t10, which occur mainly in partially hydrogenated industrial fat, t11 is partially metabolized into c9,t11 CLA via Δ9-desaturation. This is the major metabolic criterion used to differentiate between t11 and other trans C18:1. t11 indicates health beneficial effects in several studies. Moreover, CLA in milk fat is associated with the prevention of allergy and asthma. An analysis of the few studies relating to R-TFA alone makes clear that no convincing adverse physiological effect can be attributed to R-TFA. Only extremely high R-TFA intakes cause negative change in blood lipids. In conclusion, in most European countries, the intake of R-TFA is assessed as being low to moderate. Restriction of R-TFA would unjustifiably represent a disadvantage for organic farming of milk.

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Section: Epidemiological and Clinical Studies Concerning R-tfa Or Indmentioning

confidence: 99%

Evaluation of the Impact of RuminantTransFatty Acids on Human Health: Important Aspects to Consider

Kuhnt

Degen

Jahreis

2015

Critical Reviews in Food Science and Nutrition

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“…In recent decades, there has been an increased presence of hydrogenated vegetable fat and saturated fat in foods [23] accompanied by a significant reduction in the consumption of foods rich in essential fatty acids (EFA) [24]. Regular consumption of TFA may eventually result in a loss of EFA, with unpredictable impacts on human health, because TFA derivatives may be incorporated into membrane phospholipids [25] and alter membrane fluidity, plasticity and neurotransmission [26,27].…”

Section: Introductionmentioning

confidence: 99%

Chronic consumption of trans fat can facilitate the development of hyperactive behavior in rats

Pase

Trevizol

Kuhn

et al. 2015

Physiology & Behavior

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“…Studies have now started differentiating the effects of iTFA and rTFA on health indices 10 [236,[245][246][247][248][249]. A meta-analysis of 8 prospective cohort studies showed a trend towards a 11 positive association with coronary heart disease and higher intakes of iTFA but not rTFA 12 [247].…”

Section: Are All Saturated Fatty Acids Equal? 28mentioning

confidence: 99%

Should the pharmacological actions of dietary fatty acids in cardiometabolic disorders be classified based on biological or chemical function?

Poudyal

Brown

2015

Progress in Lipid Research

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Impact of trans fatty acids of ruminant origin compared with those from partially hydrogenated vegetable oils on CHD risk

Cited by 37 publications

References 54 publications

Evaluation of the Impact of RuminantTransFatty Acids on Human Health: Important Aspects to Consider

Evaluation of the Impact of RuminantTransFatty Acids on Human Health: Important Aspects to Consider

Chronic consumption of trans fat can facilitate the development of hyperactive behavior in rats

Should the pharmacological actions of dietary fatty acids in cardiometabolic disorders be classified based on biological or chemical function?

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