Impact of Tibial Runoff on Outcomes of Endovascular Treatment for Femoropopliteal Atherosclerotic Lesions

Abstract

The patients with poor runoff showed significantly lower amputation-free survival and freedom from ischemia. In poor tibial runoff limbs with critical limb ischemia or tissue loss, BTK intervention did not demonstrate additional significant beneficial outcomes; however, there was a minor trend of longer lasting freedom from ischemia after concomitant BTK intervention.

Comparison between paclitaxel-coated balloon and standard uncoated balloon in the treatment of femoropopliteal long lesions in diabetics

“…Atherosclerotic diseases may include femoropopliteal artery stenosis or occlusion. [1,2] Percutaneous transluminal angioplasty (PTA) is an effective and minimally invasive treatment strategy for atherosclerotic femoropopliteal artery stenosis/occlusion disease. [3–5] Balloon angioplasty is a widely used technique in the management of occlusive disease in almost all arterial segments.…”

Cardiovascular and Limb Events Following Endovascular Revascularization Among Patients ≥65 Years Old: An American College of Cardiology PVI Registry Analysis

“… 1 Certain characteristics have been demonstrated to confer higher risk of major adverse cardiovascular events (MACE) or major adverse limb events (MALE) following PVI, such as diabetes, 2 , 3 , 4 chronic kidney disease (CKD), 5 , 6 concomitant coronary artery or cerebrovascular disease, 7 , 8 and certain lesion characteristics. 2 , 9 , 10 , 11 However, the relationships between these factors have not been well explored in high‐quality, multi‐center data sets, with most reports focusing instead on the contribution of isolated high‐risk features to outcomes. 3 , 4 , 6 , 9 , 10 , 11 Other studies have described contributions of multiple risk factors, though with limited outcomes, single center data, or with minimal PAD‐ and procedure‐specific data.…”

“… 2 , 9 , 10 , 11 However, the relationships between these factors have not been well explored in high‐quality, multi‐center data sets, with most reports focusing instead on the contribution of isolated high‐risk features to outcomes. 3 , 4 , 6 , 9 , 10 , 11 Other studies have described contributions of multiple risk factors, though with limited outcomes, single center data, or with minimal PAD‐ and procedure‐specific data. 5 , 12 , 13 , 14 , 15 This can lead to attributing risk to a comorbidity (eg, diabetes) while missing the possible intermediary steps by which that characteristic may contribute to events (for example, through the association between diabetes and worse infrapopliteal runoff).…”

Prevalence and Outcomes of Endovascular Infrapopliteal Interventions for Intermittent Claudication

“…Prior studies have shown improved patency and limb salvage with better runoff scores. 12,13 However, most of these studies were in patients with CLTI and are not necessarily generalizable to the claudicant population where further study is required. Finally, progression to minor and/or major amputation after an intervention for IC, especially within one year, should be considered a failure of treatment and bring into question the overall indication for the initial PVI.…”