Impact of thrombus aspiration during primary percutaneous coronary intervention on mortality in ST-segment elevation myocardial infarction

Abstract

This study of real-world, unselected STEMI patients demonstrates that thrombus aspiration during PPCI is associated with a significant reduction in mortality, especially in those with a short total ischaemic time. These findings support the use of thrombectomy during PPCI in this group of patients.

Thrombus aspiration in ST-elevation myocardial infarction: Does it actually impact long-term outcome?

“…Similar results were reported by Kilic et al [21]. On the contrary, in two large real world registries, thrombus aspiration was associated with long-term clinical benefit [22,23]. Data from randomized trials are even more inconclusive and meta-analyses are not able to shed light on the real efficacy of thrombectomy.…”

Shock-index as a novel predictor of long-term outcome following primary percutaneous coronary intervention

“…16 All other clinical and interventional parameters have been described in our previous publications. 20,21 Statistics Continuous variables are presented as median and interquartile range (IQR: 25 th -75 th ). Categorical variables were compared by the χ 2 test, and continuous variables by the independent t-test or Mann-Whitney U test as appropriate.…”

Thrombus Aspiration Therapy and Coronary Thrombus Components in Patients with Acute ST-Elevation Myocardial Infarction

“…recently analyzed prospective data for 2,567 consecutive STEMI patients treated with p-PCI and reported that thrombectomy was associated with significant reductions in in-hospital mortality (OR 0.51, 95% CI 0.29-0.93, p = 0.027) and long-term mortality (OR 0.69, 95% CI 0.48-0.96, p = 0.028) during a mean follow-up of 9.9±3.8 months 72) . Based on these findings, if not anatomically contraindicated, adjunctive manual thrombectomy devices should be widely and routinely used in STEMI patients undergoing p-PCI.…”