Impact of the short-term, intense exercise on postprandial glycemia in type 2 diabetic patients treated with gliclazide

Exercising for Metabolic Control: Is Timing Important?

“…The remaining 18 studies investigated the effect of exercise on postprandial events, modulating some parameters related to meals and exercise (i.e. exercise intensity and duration, meal size and composition) [36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53]. …”

“…When comparing 15-min bouts with 40-min bouts, the hypoglycemic effect appears to be proportional to the duration in the same way it is proportional to the intensity, leading to the suggestion that this lowering effect is primarily determined by energy expenditure during exercise [49]. Furthermore, those who might be benefiting more from 30–40 min of moderate-intensity exercise, or shorter-duration but higher-intensity exercise, are individuals showing more elevated glycemic responses at rest [49,52] and sedentary, middle-aged subjects, the latter compared to trained, young subjects [43]. Even more interesting is the fact that the glucose-lowering effect of postmeal exercise is reported to be comparable to that of hypoglycemic drugs [43].…”

“…Even more interesting is the fact that the glucose-lowering effect of postmeal exercise is reported to be comparable to that of hypoglycemic drugs [43]. A more vigorous postprandial exercise has been reported to transiently increase blood glucose values compared to pre-exercise [52]. In contrast, Charlot et al [37] reported that 75 min of high-intensity cycling, compared to rest, yield sustained lower glycemia throughout the exercise session and may also exert an influence on the following meal, delaying peak postlunch glycemia with no significant difference in total glucose AUCs.…”

Post-Meal Exercise may Attenuate the Glycemic Response to a Carbohydrate Load: Important Implications for Adults who are Obese, with Pre-Diabetes or Diabetes, and/or At-Risk for Dementia

“…50 However, compliance with current exercise recommendations is poor, with self-reported compliance rates of about 35% for those with T2DM. 51 Emerging evidence [52][53][54][55][56][57][58][59] suggests that a short bout of post-meal exercise in particular can attenuate the spike in BG after consumption of carbohydrates, which may be advantageous for those with and without diabetes, including those with dementia. Knowing that a short bout of exercise after consumption of a carbohydrate load could specifically decrease the spike in BG after carbohydrate consumption may be more motivating for compliance than exercising for general improvements in glycemic control.…”

“…57 They found that post-meal exercise resulted in lower plasma glucose levels at the end of exercise compared to values at the same time point when subjects had walked pre-meal. Additional studies found post-meal exercise (1 hour moderate exercise 58 or a short bout of intense exercise) 59 resulted in reduced hyperglycemia in those with T2DM; however, the exercise did not commence immediately after meal consumption. Additionally, subjects with higher pre-exercise BG levels in both studies benefited the most from post-meal exercise.…”