Impact of the serum albumin level on acute kidney injury after cerebral artery aneurysm clipping

Bang, Ji‐Yeon; Kim, Seon‐Ok; Kim, Sae-Gyeol; Song, Jun-Gol; Kang, Jiwon; Kim, Jong-Wook; Ha, Seungil

doi:10.1371/journal.pone.0206731

Cited by 6 publications

(4 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Finally, it has been reported that elevated RDW is associated with malnutrition 36. And hypoalbuminemia, a marker of malnutrition, is an independent risk factor of AKI in various clinical settings [37][38][39]. Therefore, malnutrition is another bridge to understand the relationship between elevated RDW and AKI.Previous studies had explored the prognostic value of RDW in TBI patients with contradictory results.…”

mentioning

confidence: 99%

The predictive value of RDW in AKI and mortality in patients with traumatic brain injury

Wang

et al. 2020

Clinical Laboratory Analysis

View full text Add to dashboard Cite

Background Red blood cell distribution width (RDW) has been validated valuable in predicting outcome and acute kidney injury (AKI) in several clinical settings. The aim of this study was to explore whether RDW is associated with outcome and AKI in patients with traumatic brain injury (TBI). Methods Patients admitted to our hospital for TBI from January 2015 to August 2018 were included in this study. Multivariate logistic regression analysis was performed to identify risk factors of AKI and outcome in patients with TBI. The value of RDW in predicting AKI and outcome was evaluated by receiver operating characteristic (ROC) curve. Results Three hundred and eighteen patients were included in this study. The median of RDW was 14.25%. We divided subjects into two groups based on the median and compared difference of variables between two groups. The incidence of AKI and mortality was higher in high RDW (RDW > 14.25) group (31.45% vs 9.43%, P < .001; 69.81% vs 29.56%, P < .001). Spearman's method showed RDW was moderately associated with 90‐day Glasgow Outcome Scale (GOS) (P < .001). In multivariate logistic regression analysis, RDW, lymphocyte, chlorine, and serum creatinine were risk factors of AKI. And Glasgow Coma Scale (GCS), glucose, chlorine, AKI, and RDW were risk factors of mortality. The area under the ROC curve (AUC) of RDW for predicting AKI and mortality was 0.724 (0.662‐0.786) and 0.754 (0.701‐0.807), respectively. Patients with higher RDW were likely to have shorter median survival time (58 vs 70, P < .001). Conclusions Red blood cell distribution width is an independent risk factor of AKI and mortality in patients with TBI.

show abstract

mentioning

confidence: 99%

The predictive value of RDW in AKI and mortality in patients with traumatic brain injury

Wang

et al. 2020

Clinical Laboratory Analysis

View full text Add to dashboard Cite

show abstract

“…Serum albumin is related to cerebral ischemia ( Turhan et al, 2006 ), Alzheimer’s disease ( Skillbäck et al, 2017 ; Bode et al, 2018 ; Kim et al, 2020 ), Crohn’s disease ( Su et al, 2019 ), liver cirrhosis ( Chen et al, 2011 ; Oettl et al, 2013 ; Arroyo et al, 2014 ), chronic heart failure ( Jabbour et al, 2014 ), acute kidney injury ( Bang et al, 2018 ; Thongprayoon et al, 2018 ; Lv et al, 2021 ), chronic kidney disease ( Stoycheff et al, 2009 ; Zhang et al, 2015 ) and other diseases; however, the relationship between serum albumin and pulmonary function is unclear. Several studies have shown that in some acute respiratory diseases that lead to reduced pulmonary function, such as acute respiratory distress and acute lung, serum albumin increases capillary permeability, causing it to leak from blood vessels into tissue fluid or to escape into the alveolar space, resulting in reduced serum albumin levels ( Fanali et al, 2012 ).…”

Section: Discussionmentioning

confidence: 99%

Supplementation of serum albumin is associated with improved pulmonary function: NHANES 2013–2014

et al. 2022

View full text Add to dashboard Cite

Background: The serum albumin level is reflective of the function of multiple organs, such as the liver and kidneys. However, the association between serum albumin and pulmonary function is unclear; therefore, this study aimed to determine the relationship between pulmonary function and serum albumin, including the threshold of serum albumin at the changes of the pulmonary function in the total population and in different strata of population.Methods: In this cross-sectional study, We examined the relationship between serum albumin and two independent indicators of pulmonary function: forced vital capacity (FVC) and forced expiratory volume in one second (FEV 1), using data from National Health and Nutrition Examination Survey (NHANES 2013–2014) (n = 3286). We used univariate analysis, stratified analysis, and multiple regression equation analysis to examine the correlation between serum albumin levels and FVC and FEV 1, and performed smoothed curve fitting, threshold effect, and saturation effect analysis (for stratification) to determine the threshold serum albumin level at which FVC and FEV 1 begin to change.Results: The adjusted smoothed curve fit plot showed a linear relationship between serum albu-min levels and FVC: for every 1 g/dl increase in the serum albumin level, FVC increased by 80.40 ml (11.18, 149.61). Serum albumin and FEV 1 showed a non-linear relationship. When serum al-bumin reached the inflection point (3.8 g/dl), FEV 1 increased with increasing serum albumin and the correlation coefficient β was 205.55 (140.15, 270.95).Conclusion: Serum albumin is a core indicator of liver function, and abnormal liver function has a direct impact on pulmonary function. In the total population, serum albumin levels were linearly and positively correlated with FVC. Above 3.6 g/dl, serum albumin was positively correlated with FEV 1. Based on the total population and different population strata, this study revealed a positive association between the serum albumin level and pulmonary function, and identified the threshold of serum albumin when Indicators of pulmonary function tests starts to rise, providing a new early warning indicator for people at high risk of pulmonary insufficiency and has positive implications for the prevention of combined respiratory failure in patients with liver insufficiency.

show abstract

“…Low preoperative serum albumin levels are associated with perioperative complications including AKI [ 23 ]. Albumin is a potential natural antioxidant that acts as a core extravascular source of reduced sulfhydryl groups, so-called thiols, that scavenge reactive oxygen and nitrogen species; thus, hypoalbuminemia can cause postoperative AKI [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

Comparison of the Effects of Laparoscopic and Open Surgery on Postoperative Acute Kidney Injury in Patients with Colorectal Cancer: Propensity Score Analysis

Sim

Kang

Bang

et al. 2021

JCM

Self Cite

View full text Add to dashboard Cite

Postoperative acute kidney injury (AKI) is a serious complication that increases patient morbidity and mortality. However, few studies have evaluated the effect of laparoscopic surgery on postoperative AKI. This study compared the incidence of postoperative AKI between laparoscopic and open surgery in patients with colorectal cancer. This study retrospectively analyzed 3637 patients who underwent colorectal cancer surgery between June 2008 and February 2012. The patients were classified into laparoscopic (n = 987) and open (n = 2650) surgery groups. We performed multivariable regression analysis to assess the risk factors for AKI and propensity score matching analysis to compare the incidence of AKI between the two groups. We also assessed postoperative intensive care unit (ICU) admission, complications, hospital stay, and 1-year mortality. We observed no significant differences in the incidence of postoperative AKI between the two groups before (8.8% vs. 9.1%, p = 0.406) and after (8.8% vs. 7.7%, p = 0.406) matching. Laparoscopic surgery was not associated with AKI even after adjusting for intraoperative variables (adjusted odds ratio (OR): 1.17, 95% confidence interval (CI): 0.84–1.62, p = 0.355). Body mass index, diabetes mellitus, hypertension, and albumin were risk factors for AKI. ICU admission (0.6% vs. 2.5%, p = 0.001), complications (0.2% vs. 1.5%, p = 0.002), hospital stay (6.89 days vs. 8.61 days, p < 0.001), and 1-year mortality (0.1% vs. 0.9%, p = 0.021) were significantly better in the laparoscopic than in the open group. The incidence of postoperative AKI did not differ significantly between laparoscopic and open surgery. However, considering its better surgical outcomes, laparoscopic surgery may be recommended for patients with colorectal cancer.

show abstract

Impact of the serum albumin level on acute kidney injury after cerebral artery aneurysm clipping

Cited by 6 publications

References 28 publications

The predictive value of RDW in AKI and mortality in patients with traumatic brain injury

The predictive value of RDW in AKI and mortality in patients with traumatic brain injury

Supplementation of serum albumin is associated with improved pulmonary function: NHANES 2013–2014

Comparison of the Effects of Laparoscopic and Open Surgery on Postoperative Acute Kidney Injury in Patients with Colorectal Cancer: Propensity Score Analysis

Contact Info

Product

Resources

About