2011
DOI: 10.1136/heartjnl-2011-300197
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Impact of the permanent ventricular pacing site on left ventricular function in children: a retrospective multicentre survey

Abstract: In children with isolated AV block, permanent ventricular pacing site is an important determinant of LV function, with LVFS being significantly higher with LV pacing than with RV pacing.

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Cited by 67 publications
(33 citation statements)
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“…adults demonstrated that chronic RV pacing might result in electromechanical dys-synchrony, leading to adverse LV remodeling with LV dilatation and asymmetric hypertrophy. [28][29][30] Up to 30% of patients develop dilated cardiomyopathy, 29 and 5% to 10% develop heart failure. 30 These unfavorable consequences have produced considerable interest in alternative pacing sites.…”
Section: Electrical Remodelingmentioning
confidence: 99%
See 1 more Smart Citation
“…adults demonstrated that chronic RV pacing might result in electromechanical dys-synchrony, leading to adverse LV remodeling with LV dilatation and asymmetric hypertrophy. [28][29][30] Up to 30% of patients develop dilated cardiomyopathy, 29 and 5% to 10% develop heart failure. 30 These unfavorable consequences have produced considerable interest in alternative pacing sites.…”
Section: Electrical Remodelingmentioning
confidence: 99%
“…[28][29][30] Up to 30% of patients develop dilated cardiomyopathy, 29 and 5% to 10% develop heart failure. 30 These unfavorable consequences have produced considerable interest in alternative pacing sites. Very recently, Salameh et al described the effects of LV apical pacing as opposed to RV free wall pacing on ventricular synchrony, function, and ultrastructure in a mini-pig model mimicking chronic pacing for complete AV block started during early childhood.…”
Section: Electrical Remodelingmentioning
confidence: 99%
“…A recent multicentre study showed that left ventricular pacing was associated with better systolic function than right ventricular pacing, 67 and a useful review put the problems of pacing in children into context.…”
Section: Catheter Interventionmentioning
confidence: 99%
“…Patients with a CIED had greater cardiac comorbidity than those without a CIED, although CIED implantation was associated with a 46% reduction in mortality (HR 0.54, 95% CI 0.35 to 0.82; p=0.004). In another observational study of the impact of the ventricular pacing site on LV function in children with AV block, van Geldrop et al (82) found that LV fractional shortening was significantly higher with LV pacing than with RV pacing.…”
Section: Heart Block and Pacemakersmentioning
confidence: 99%