By using the specific co-NBI and ctr-NBI systems on EAST, an alternating E × B flow shear discharge has been performed to study the impact of the E × B flow shear on ballooning-driven ELM at a fixed high collisionallity (ν * ∼ 2.3). The results reveal that the increased E×B flow shear can significantly mitigate the ELM, or even totally suppress the ELM when the shear is large enough. Our simulations with BOUT++ support the observations on EAST, and further indicates that the increased E × B can both reduce the linear growth rate of ballooning mode and shorten its growth time (phase coherence time, PCT) . The enhanced nonlinear interactions shorten the PCT of ballooning mode, which is validated by the bispectrum study on EAST. All those studies suggest a new way to control the ELM.