Impact of the human papillomavirus (HPV) vaccine supply shortage on Tanzania’s national HPV vaccine introduction

Li, Anyie J.; Kyesi, Furaha; Mwengee, William; Mphuru, Alex; Giattas, Mary Rose; Shayo, Berrington; Nshunju, Raphael; Lyimo, Dafrossa; Loharikar, Anagha

doi:10.1016/j.vaccine.2021.01.036

Cited by 8 publications

(11 citation statements)

References 7 publications

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“…However, due to limited global vaccine supply, Tanzania was only able to vaccinate a single-age cohort of girls. 14-year-old girls were chosen for this temporary single-age cohort vaccination in order to expand the reach of HPV vaccination as these girls would no longer be age eligible (≥15 years old) in the future [ 14 ]. Kilimanjaro region continued vaccinating 9-year-old girls following their demonstration project.…”

Section: Introductionmentioning

confidence: 99%

National introduction of human papillomavirus (HPV) vaccine in Tanzania: Programmatic decision-making and implementation

Mphuru¹,

Kyesi

et al. 2022

Vaccine

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Section: Introductionmentioning

confidence: 99%

National introduction of human papillomavirus (HPV) vaccine in Tanzania: Programmatic decision-making and implementation

Mphuru¹,

Kyesi

et al. 2022

Vaccine

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“…There may be local shortages and surpluses caused by the unbalanced distribution of vaccines in some regions [17] In conclusion, the supply of vaccines in China's national immunization program can meet the demand of vaccines, but some vaccines are at risk of shortage. Reasons for these possible shortages were multi-factorial and included companies leaving the vaccine market, manufacturing or production problems, and Changes in vaccine procedures for immunization programmes [18,19]. In 2020, China had faced with the serious threat of novel coronavirus epidemic, and the production and distribution of vaccines will be affected by the shutdown.…”

Section: Discussionmentioning

confidence: 99%

Analysis of Vaccine Supply and Demand in National Immunization Program for Children and the need for Establishing Vaccine Stockpiles in China

Jian

Liu

et al. 2021

Preprint

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Introduction The number of vaccines used in China's childhood immunization program had continued to increase, from four in 1978 to ten in 2019. We described the supply and demand of vaccines, and compared the ratio of vaccine supply and demand of each vaccine to illustrate the shortage of vaccines and the need of vaccine stockpiles in China. Methods We downloaded the manufacturers supplying vaccines and the vaccination requirements for the national immunization program for children from 2016 to 2019 in the National Immunization Program Information system, as well as the batch issue data of biological products from the official website of China Academy of Food and Drug Control (CFDA). Vaccine prices were obtained from Chinese Central Government Procurement (CCGP).The demand, supply, and the ratio of vaccine supply and demand of each vaccine were calculated respectively. Results On average, five out of ten vaccines were supplied by three or more enterprises, three kinds of vaccines were supplied by two enterprises and two kinds of vaccines were supplied only by one enterprise between 2016 to 2019. The ratio of vaccine supply and demand of Diphtheria-tetanus and Group A meningitis polysaccharide were 79.52% and 67.99% respectively, with a potential shortage. There were three vaccines with a supply-demand ratio below 80% in 2016–2018, and five in 2019. The number of potential vaccine shortage was increasing. The average price of vaccines with potential shortage was $ 0.28. The average price of other vaccines without shortage was $ 1.8. Conclusions Most vaccines used in the childhood immunization program are available to meet demand, but there are also some vaccines with the risk of shortage and the number of vaccines with the risk of shortage tends to increase. The next step is to develop a national stockpiling mechanism to avoid a shortage of vaccines.

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“…Worldwide, more than 80% of cervical cancer fatalities and new cases occur in low-and middle-income nations. 18 Middle income nations, where screening and vaccination are currently the main means of prevention. The bivalent vaccine from Cervarix and the tetravalent and nine-valent vaccines from Gardasil are the three most widely used HPV vaccines on the market.…”

Section: The Hpv Vaccine's Research and Development Have Reached A Ma...mentioning

confidence: 99%

Challenges of hesitancy in human papillomavirus vaccination: Bibliometric and visual analysis

Deng

Shen

et al. 2023

Health Planning & Management

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BackgroundHuman papillomavirus (HPV) vaccine has immense research value in the prevention of related tumours. A huge body of work has been published in this field, which may pose difficulties for researchers aiming to investigate all the available information. However, bibliometrics can provide deep insights into this research field.ObjectiveWe aimed to study HPV vaccine development, visually analyse the development status, trends, research hotspots, and frontiers of this field, and provide a reference for research on it.MethodsArticles were acquired from the Web of Science Core Collection. VOS viewer and CiteSpace software were used to analyse publication growth, country/region, institution, journal distribution, author, reference, and keywords, and collected burst keyword words to display research hotspots.ResultsA total of 4831 references were obtained, and the annual number of publications increased fluctuating over the past decade. The United States of America ranked at the top in terms of percentage of articles. The institution with the highest number of research publications in this field was the Centers for Disease Control and Prevention. The most productive and frequently cited authors was Lauri E Markowitz. The journal with the most publications in this field was Vaccine, and the most influential journal was Paediatrics. The most frequently cited reference was ‘A 9‐Valent HPV Vaccine against Infection and Intraepithelial Neoplasia in Women’. Burst detection analysis of top keywords showed that ‘national immunisation survey’, ‘social media’, and ‘hesitancy’ are the current research frontiers in this field.ConclusionThis study provides useful information for acquiring knowledge on HPV vaccine. Research on solving the hesitation of HPV vaccination will become an academic trend in this field, which can offer guidance for more extensive and in‐depth studies in the future.

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Impact of the human papillomavirus (HPV) vaccine supply shortage on Tanzania’s national HPV vaccine introduction

Cited by 8 publications

References 7 publications

National introduction of human papillomavirus (HPV) vaccine in Tanzania: Programmatic decision-making and implementation

National introduction of human papillomavirus (HPV) vaccine in Tanzania: Programmatic decision-making and implementation

Analysis of Vaccine Supply and Demand in National Immunization Program for Children and the need for Establishing Vaccine Stockpiles in China

Challenges of hesitancy in human papillomavirus vaccination: Bibliometric and visual analysis

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