Impact of the host immune response on the development of equine herpesvirus myeloencephalopathy in horses
K. S. Giessler,
L. S. Goehring,
S. I. Jacob
et al.
Abstract:Herpesviruses establish a well-adapted balance with their host’s immune system. Despite this co-evolutionary balance, infections can lead to severe disease including neurological disorders in their natural host. In horses, equine herpesvirus 1 (EHV-1) causes respiratory disease, abortions, neonatal foal death and myeloencephalopathy (EHM) in ~10 % of acute infections worldwide. Many aspects of EHM pathogenesis and protection from EHM are still poorly understood. However, it has been shown that the incidence of… Show more
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