Impact of the delay in cryopreservation timing during biobanking procedures on human liver tissue metabolomics
Corentine Goossens,
Vincent Tambay,
Valérie-Ann Raymond
et al.
Abstract:The liver is a highly specialized organ involved in regulating systemic metabolism. Understanding metabolic reprogramming of liver disease is key in discovering clinical biomarkers, which relies on robust tissue biobanks. However, sample collection and storage procedures pose a threat to obtaining reliable results, as metabolic alterations may occur during sample handling. This study aimed to elucidate the impact of pre-analytical delay during liver resection surgery on liver tissue metabolomics. Patients were… Show more
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