Impact of the anatomical location, alcoholism and smoking on the prevalence of advanced oral cancer in Brazil

Abstract

BackgroundTo evaluate the prevalence of oral cancer in Brazil according to the clinical stage, anatomical location, alcoholism and smoking.Material and MethodsData referring to 31,217 cases of oral cancer, from 2000 to 2010, were obtained from the Integrator Module of the Hospital Registry of Cancer. Inconsistent data (“non-classified” cases) was eliminated and 21,160 cases were analyzed. The frequency distribution according to clinical stage, anatomical location, alcoholism and smoking was analyzed descriptively and through a binary logistic regression model (α<0.05). The clinical stage (dependent variable) was dichotomized in early stage (I and II) or advanced stage (III and IV). The year of diagnosis, anatomical location and deleterious habits (alcoholism and smoking) were considered independent variables.ResultsThe most frequent characteristics were: oropharynx location (n=3856, 18.41%), clinical stage IV (n=11924, 56.09%) and combined use of alcohol and tobacco (n=19226; 61.59%). The year 2009 (p<0.01, PR = 1.162, CI-95%=1.053-1.283) and location at the base of tongue (p<0.01, PR = 2.485, CI-95% = 2.182-2.807) presented a higher prevalence ratio for advanced stage oral cancer. The combined use of alcohol and tobacco showed a higher prevalence rate for the advanced clinical stage of cancer (p<0.01, PR =1.449, CI-95%=1.382-1.520) if compared to individuals without habits, or just alcoholics.ConclusionsHigher prevalence of advanced stage of oral cancer is related to the localization at the base of the tongue and to the concomitant use of alcohol and tobacco. Therefore, it can be suggested that all these characteristics lead to a worse prognosis of oral cancer. Key words:Oral cancer, neoplasm staging, alcoholism, tobacco use disorder.

Quality of information about oral cancer in Brazilian Portuguese available on Google, Youtube, and Instagram

“…In Brazil, most cases of oral cancer are diagnosed at an advanced clinical stage, which results in poor prognosis and a high mortality rate (17). Among the reasons for the delay in diagnosis are the lack of available information about the disease and its low quality (3,4).…”

Public Oral Health Services Coverage and Socioeconomic Indicators’ Effect on The Number of Hospitalized Cases of Oral Cancer in Brazil

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Multimodal widefield fluorescence imaging with nonlinear optical microscopy workflow for noninvasive oral epithelial neoplasia detection: a preclinical study

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