Abstract:Structure and functionality of molecular layers play a crucial role in determining the outcome of analyte-receptor interactions on affinity biosensors. The control over the structure of these molecular layers gives an independent means to enhance the sensor performance. Here we study the impact of the length and flexibility of molecular tethers on analyte capture by tethered receptors on quartz crystal microbalance and surface plasmon resonance sensors. Our results show clear enhancement of analyte-receptor in… Show more
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