Impact of tafamidis on myocardial function and CMR tissue characteristics in transthyretin amyloid cardiomyopathy
Stephan Dobner,
Benedikt Bernhard,
Lorenz Ninck
et al.
Abstract:AimsTafamidis improves clinical outcomes in transthyretin amyloid cardiomyopathy (ATTR‐CM), yet how tafamidis affects cardiac structure and function remains poorly described. This study prospectively analysed the effect of tafamidis on 12‐month longitudinal changes in cardiac structure and function by cardiac magnetic resonance (CMR) compared with the natural course of disease in an untreated historic control cohort.Methods and resultsATTR‐CM patients underwent CMR at tafamidis initiation and at 12 months. Unt… Show more
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