Impact of surgical weight loss on novel P‐wave‐related variables which are nominated as predictors of atrial arrhythmias

Abstract

Background Bariatric surgery has been associated with reduced cardiovascular mortality and morbidity in obese patients. In this study, we aimed to evaluate the alterations of novel P‐wave related atrial arrhythmia predictors in patients who achieved effective weight loss with bariatric surgery. Methods The study included 58 patients who underwent bariatric surgery. We measured heart rate, PR, P wave (PW) max, PW min, Average P axis, P wave peak time (PWPT) in lead D2 and lead V1, terminal force in lead V1 (V1TF), and we estimated P wave dispersion (PWdis) interval both pre‐operation and 6 months after operation. Results Heart rate, PR, PW max, PW min, PWdis, Average P axis, PWPTD2, PWPTV1 and V1TF values, which were close to the upper limit in the pre‐op period, showed statistically significant decreases at 6 months after the operation. The most prominent changes were observed in PW dis (51.15 ± 9.70 ms vs. 48.79 ± 9.50 ms, p = .010), PWPTD2 (55.75 ± 6.91 ms vs. 50.59 ± 7.67 ms, p < .001), PWPTV1 (54.10 ± 7.06 ms vs. 48.05 ± 7.64 ms, p < .001) and V1TF (25 [43.1%] vs. 12 [20.7%], p < .001). Conclusions The results of our study indicated that bariatric surgery has positive effects on the regression of ECG parameters which are predictors of atrial arrhythmias, particularly atrial fibrillation (AF).

The effect of empagliflozin on P wave peak time and other P wave parameters in patients with diabetes mellitus

“…showed a reduction in PWdis in obese patients after weight loss, and they emphasize that this finding could be associated with a lower risk of PAF 39 . In addition, a recent study examined the effect of bariatric surgery on arrhythmias associated with P waves 40 . They found similar findings to our study in terms of P wave parameters.…”

“…39 In addition, a recent study examined the effect of bariatric surgery on arrhythmias associated with P waves. 40 There are a few limitations of the study, with the most important being the sample size and follow-up period. A larger sample and longer follow-up period may have different effects on the outcomes.…”

“…Significant reductions were observed in HbA1c (p < .001), triglyceride (p < .001), and total cholesterol (p = .02) whereas hematocrit (p < .001) and platelet count (p = .001) were significantly higher. The clinical findings and laboratory parameters of the patients are shown in Table2.LA volume (42[36][37][38][39][40][41][42][43][44][45][46][47] vs. 40[33][34][35][36][37][38][39][40][41][42][43][44], p < .001), LA diameter both in parasternal long axis(38 [36.5-42] vs. 38[35][36][37][38][39][40][41], p = .001) and apical four chamber view(37 [33-41] vs. 37[30][31][32][33][34][35][36][37][38][39], p = .027) were decreased after treatment compared to baseline. E/e′ (6.8 [5.9-9.4] vs. 5.92[4.96-7.74], p = .001), systolic pulmonary arterial pressure (sPAP) (20[17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32]…”

Evaluation of the Effects of Adolescent Obesity on Electrocardiography and Pulmonary Function Tests

“…Özellikle 12 derivasyonlu elektrokardiyografi (EKG)'den elde edilen P dalga dispersiyonu, QT aralığı, düzeltilmiş QT ("Corrected" QT-QTc), QT dispersiyonu ve düzeltilmiş QT dispersiyonu, miyokardın aritmilere duyarlılığını göstermektedir ve ani kardiyak ölüm riski ile ilişkili bulunmuştur (5,6). P dalga dispersiyonu, atrial aritmi gelişimini tahmin etme araçlarından biridir ve P dalga dispersiyonunun uzaması, atrial aritmi açısından riskin artmış olduğunu gösterir (7,8).…”