Impact of Supplemental Vitamin K1 Administration on Postoperative Blood Component Requirements After Craniosynostosis Repair

Kicker, Jennifer S.; Willson, Douglas F.; Kelly, Robin L.; Jane, John A.; Roberts, Susan A.; Conaway, Mark R.

doi:10.1097/scs.0000000000000384

Cited by 1 publication

(2 citation statements)

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“…Postoperatively, 44 patients received FFP (5 mL/kg). Exclusively breastfed infants may benefit from injection vitamin K. 21…”

Section: Discussionmentioning

confidence: 99%

“…Postoperatively, 44 patients received FFP (5 mL/kg). Exclusively breastfed infants may benefit from injection vitamin K. 21 A cautious extubation of syndromic/complex patients is warranted and is should be always in the presence of an experienced anesthetist as the surgery itself may alter airway anatomy and predispose the children both to airway obstruction and desaturation. We found that patients with complex craniosynostosis have a statistically significant risk of postoperative respiratory failure leading to ventilation (p = 0.025).…”

Section: Discussionmentioning

confidence: 99%

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Comparison of Perioperative Anesthetic Concerns in Simple and Complex Craniosynostosis Cases: A Retrospective Study

Menon

Mathew

Kumar

et al. 2022

J Neuroanaesth Crit Care

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Background We compared intraoperative and postoperative anesthetic parameters between simple (S-single suture) and complex (C-more than one suture) craniosynostosis cases. Materials and Methods Data was collected from a retrospective review of anesthetic and postoperative records of patients who underwent craniosynostosis correction surgery between April 2014 and August 2019. Pearson’s chi-square and independent sample t-tests were used for analysis. Results We analyzed data of 98 patients (S-simple craniosynostosis: 40 and C-complex craniosynostosis: 58). Statistically significant differences between simple and complex cases were seen only in the incidence of difficult airway, failed extubation, and requirement of postoperative ventilation. Massive blood loss (S: 23.21 mL/kg; C: 22.71 mL/kg) and difficult airway (S: 2.04%; C: 19.39%) were the most common intraoperative adverse events encountered. Metabolic abnormalities, hemodynamic instability, and hypothermia occurred in few patients. The most common postoperative issue was pyrexia (S: 15.31%; C: 17.35%). Anemia and coagulopathy needing transfusion of blood products and vitamin K injection were seen in a significant number of cases. Three nonsyndromic patients developed seizures. Conclusion The incidence of difficult airway and failed extubation with postoperative ventilation is more frequent following surgery for complex craniosynostosis than simple craniosynostosis. Complications secondary to blood loss and airway issues were the primary cause of morbidity and mortality. A staged approach to surgical management resulted in decreased surgical blood loss among the children with complex craniosynostosis.

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“…Postoperatively, 44 patients received FFP (5 mL/kg). Exclusively breastfed infants may benefit from injection vitamin K. 21…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Comparison of Perioperative Anesthetic Concerns in Simple and Complex Craniosynostosis Cases: A Retrospective Study

Menon

Mathew

Kumar

et al. 2022

J Neuroanaesth Crit Care

View full text Add to dashboard Cite

show abstract

Impact of Supplemental Vitamin K1 Administration on Postoperative Blood Component Requirements After Craniosynostosis Repair

Cited by 1 publication

References 24 publications

Comparison of Perioperative Anesthetic Concerns in Simple and Complex Craniosynostosis Cases: A Retrospective Study

Comparison of Perioperative Anesthetic Concerns in Simple and Complex Craniosynostosis Cases: A Retrospective Study

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