“…A novel HCD, composed of 1% drug (BC), 27% sodium alginate, 2% crospovidone, 8% polyisobutylene, 25% styrene–isoprene–styrene copolymer, 25% petroleum hydrocarbon resin, and 12% liquid paraffin, was prepared using a hot melting method. Sodium alginate, crospovidone, and liquid paraffin were used as a hydrocolloid forming base [Balakrishnan et al, ; Devi et al, ], drug release‐controlling agent [Rajesh et al, ] and plasticizer [Jones et al, ], respectively and polyisobutylene, styrene–isoprene–styrene copolymer and petroleum hydrocarbon resin were used as the pressure‐sensitive adhesives and elastomers [Zohuriaan‐Mehr and Omidian, ]. These materials impart chemical inertness and excellent resistance to weathering, higher temperatures, and chemicals.…”