Impact of subcutaneous negative pressure drains on surgical wound healing in ovarian cancer

Abstract

IntroductionSubcutaneous negative pressure wound drains have been used to reduce wound complication rates in various surgical procedures. However, research on the benefits of subcutaneous drains on wound healing after ovarian cancer surgery is limited. The aim of this study was to assess the effects of subcutaneous negative pressure drains on wound healing after abdominal surgery for ovarian cancer.MethodsPatients who underwent surgery with a midline incision for ovarian cancer between February 2015 and May 2019 were retrospectively examined. Patients were divided into two groups according to the presence (group 1; n=99) or absence (group 2; n=213) of subcutaneous wound drains. The primary endpoint was the incidence of wound complications within 8 weeks after abdominal surgery. The secondary endpoints were time interval from surgery to adjuvant chemotherapy and survival.ResultsPatients in group 1 were older (mean 58.5 vs 55.4 years; p=0.02), and had higher rates of previous abdominal surgery (66.7% vs 47.9%; p=0.002), bowel surgery (47.5% vs 34.3%; p=0.026), and had a high surgical complexity score (53.5% vs 33.8%; p<0.001) compared with patients in group 2. Median body mass index was not different between the two groups: group 1, 22.9 kg/m2 (range 16.0 to 33.3) and group 2, 22.8 kg/m2 (range 16.4 to 37.5) (p=0.858). A higher rate of clear wound healing (82.8% vs 71.8%; p=0.036) and a lower rate of seroma formation (6.1% vs 16.0%; p=0.015) were observed in group 1 compared with group 2. After multivariate analysis, subcutaneous wound drain placement was identified as an independent predictive factor for preventing wound complications (adjusted odds ratio 0.43; 95% confidence interval 0.21 to 0.87). Time interval from surgery to adjuvant treatment was significantly longer in patients with wound complications than in those with clear wound healing (mean 23.6 vs 19.2 days; p=0.003). Kaplan–Meier analysis, however, showed no significant differences in progression free or overall survival between the two groups (p=0.35 and p=0.96, respectively).ConclusionThe prophylactic use of subcutaneous negative pressure drains after abdominal surgery for ovarian cancer significantly reduced the incidence of wound complications in this study.

Comparative Study between Subcuticular Suturing With and Without Drain for Wound Closure in Obese Women in Obstetric and Gynecological Operations

“…The process of as sembling and putting a subcutaneous drain increased the duration of surgery. The study group had mean duration of 1.71 hours which was more as compared to control group .In the study of Chung et al, [14] also found statistically different between groups regarding the mean operative time.…”

Risk Factors for Postoperative Incisional Infection and Anti-Infective Effects of Jefuyin Decoction in Patients With Colorectal Cancer

“…Furthermore, subcutaneous drainage was shown to be the independent protective factor against postoperative incisional infection (p < 0.05). Many previous relevant studies have suggested that subcutaneous drainage is beneficial for postoperative wound healing [18][19][20]. In addition, some patients were treated with Jefuyin Decoction fumigation.…”

Postoperative Closed-Suction Drain in Anterior Orbitotomy

“…Placement of a drain in the cavity has been shown to reduce the morbidity and complications following abdominal, plastic, and orthopedic surgery [6][7][8]. Somers et al (1992) reported that postoperative closedsuction drainage is advantageous in decreasing the incidence and degree of seroma formation after lumpectomy and axillary lymph node dissection.…”