Impact of Skeletal Muscle Measurements by Chest Computed Tomography on Survival and Postoperative Complications in Patients with Soft Tissue Sarcoma

Telli, Tuğba Akın; Bugdayci, Onur; Alan, Özkan; Sariyar, Nisanur; Işık, Selver; Arıkan, Rukiye; Yasar, Alper; Majidova, Nargiz; Celebi, Abdussamet; Erol, Bülent; Özgen, Zerrin; Köstek, Osman; Bayoğlu, İbrahim Vedat; Ercelep, Özlem; Dane, F.; Yumuk, Perran Fulden

doi:10.1080/01635581.2022.2063349

Cited by 2 publications

(2 citation statements)

References 20 publications

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“…Many reports have shown that sarcopenia is closely related to the prognosis of patients with various malignant tumors. [ 3 , 6 – 11 , 13 , 19 – 21 ] However, different pathological types of sarcomas are not identical in treatment and prognosis, so we conducted a study on the exact pathological type of sarcomas and drew relevant conclusions. Meanwhile, the effect of sarcopenia on the post-surgical outcomes of patients with liposarcoma undergoing en bloc compartment resection has not been reported.…”

Section: Discussionmentioning

confidence: 99%

“…However, some publications explored the relationship between sarcopenia and clinical outcomes among patients with sarcoma; one reported that there was no relationship between psoas cross-sectional area and clinical outcomes after soft tissue resection [6]. The others demonstrated that sarcopenia was independently associated with poorer long-term prognosis in sarcoma [3,[7][8][9][10][11], and lower psoas muscle attenuation was associated with higher mortality [8,12].…”

Section: Introductionmentioning

confidence: 99%

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Sarcopenia is associated with worse surgical complications but not relapse-free survival and overall survival in patients with retroperitoneal liposarcoma

Zhao

Fang

et al. 2022

World J Surg Onc

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Objective This investigation aimed to explore the relationship between sarcopenia and severe postoperative complications, relapse-free survival (RFS), and overall survival (OS) in patients with retroperitoneal liposarcoma (RLPS). Material and methods This retrospective study included 72 RLPS patients (47 men, 25 women; mean age, 57.49 years, SD 10.92) who had abdominal CT exams. Clinical information was recorded, including RLPS characteristics (histologic subtypes, grade, size), laboratory assessment (ALB, PALB, A/G, Hb, SCr), relapse-free survival, overall survival, and postoperative complications. The relationships between those variables and RFS and OS were analyzed using Cox proportional hazard models. Results There were 8 severe postoperative complications (Clavien-Dindo grade > 2). The chi-square test showed sarcopenia was associated with severe postoperative complications (P = 0.011). In multivariate analysis, sarcopenia was not associated with relapse-free survival (P = 0.574) and overall survival (P = 0.578). Conclusions Sarcopenia predicts worse surgical complications but does not affect relapse-free survival and overall survival.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Sarcopenia is associated with worse surgical complications but not relapse-free survival and overall survival in patients with retroperitoneal liposarcoma

Zhao

Fang

et al. 2022

World J Surg Onc

View full text Add to dashboard Cite

show abstract

Sarcopenia is associated with worse surgical complications but not relapse-free survival and overall survival in patients with retroperitoneal liposarcoma

Zhao

Fang

et al. 2022

Preprint

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Objective This investigation aimed to explore the relationship between sarcopenia and severe postoperative complications, relapse-free survival(RFS), and overall survival(OS) in patients with retroperitoneal liposarcoma (RLPS). Material and methods This retrospective study included 72 RLPS patients (47 men, 25 women; mean age, 57.49 years, SD 10.92) who had abdominal CT exams. Clinical information was recorded, including RLPS characteristics (histologic subtypes, grade, size), laboratory assessment (ALB, PALB, A/G, Hb, SCr), relapse-free survival, overall survival, and postoperative complications. The relationships between those variables and RFS and OS were analyzed using Cox proportional hazard models. Results There were 8 severe postoperative complications (Clavien-Dindo grade > 2). The Chi-square test showed sarcopenia was associated with severe postoperative complications (P = 0.011). In multivariate analysis, sarcopenia was not associated with relapse-free survival (P = 0.574) and overall survival (P = 0.578). Conclusions Sarcopenia predicts worse surgical complications but does not affect relapse-free survival and overall survival.

show abstract

Impact of Skeletal Muscle Measurements by Chest Computed Tomography on Survival and Postoperative Complications in Patients with Soft Tissue Sarcoma

Cited by 2 publications

References 20 publications

Sarcopenia is associated with worse surgical complications but not relapse-free survival and overall survival in patients with retroperitoneal liposarcoma

Sarcopenia is associated with worse surgical complications but not relapse-free survival and overall survival in patients with retroperitoneal liposarcoma

Sarcopenia is associated with worse surgical complications but not relapse-free survival and overall survival in patients with retroperitoneal liposarcoma

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