Impact of shift work on sleep problems, hormonal changes, and features of metabolic syndrome in a sample of Egyptian industrial workers

The Impact of Shift-Work and Night Shift-Work on Thyroid: A Systematic Review

“…Thyroid hormonal alterations were also investigated in shift-workers engaged in different industrial sectors, although with conflicting results. Among male workers employed in a rubber and ceramics Egyptian industry, who have been performing fixed morning-, afternoon-or night shifts for at least 2 years, those who were employed in night shifts had significantly higher levels of TSH than those who were employed in other schedules [28]. Night shift resulted as an independent predictor of TSH hormonal changes.…”

“…Overall, our search retrieved a total of 13 articles suitable for review ( Figure 1). Most of the reviewed studies assessed the association between shift-work and night-work and thyroid hormonal changes in different occupational settings [20][21][22][23][24][25][26][27][28][29] ( Table 1). Only a few publications focused on possible clinical adverse outcomes [26,[30][31][32].…”

“…The determination of serum TSH concentrations has been employed as a specific and sensitive measure for the early detection of endocrine disorders. Different investigations performed on healthcare employees demonstrated that night shift-work could be related to higher levels of TSH serum levels in involved workers, although concentrations were included in a physiological range [21,22,24,[26][27][28]. Interestingly, this effect was evident for any type of shift-working schedule considered, such as to have been involved in two consecutive night shifts before entry the study day [21], to have been performing more than 3 nights a week, for at least 1 year [27], as well as to have been engaged in night-, or 24-h on-call-duties [22,24].…”

Relationship between the night shift work and thyroid disorders: A systematic review and meta-analysis

“…The studies included for the metaanalysis show different results as for the duration of the shift working. Shaker et al (2018) have compared the night and the day shift workers, with a shift working history averaging around 18.9 years for both the groups of subjects, whereas in the study of Moon et al (2016), the average duration of the shift working was five years. Harbeck et al (2015) have compared a 24-hour on-call shift with 7-hour day shift participants, but the study did not indicate the past shift working history for both groups.…”

“…have assessed the prevalence of thyroid diseases, whileKorompeli et al (2009) have assessed T3 and T4 concentrations.Outcomes. Thyroid stimulating hormone (TSH) is the variable eligible for the meta-analysis, because it is presented in four papers of the six, i.e Shaker et al (2018)Moon et al (2016);Harbeck et al (2015);Korompeli et al (2009).…”