Impact of Septoplasty on Mean Platelet Volume Levels in Patients With Marked Nasal Septal Deviation

Sağıt, Mustafa; Korkmaz, Ferhat; Kavugudurmaz, Mustafa; Somdas, Mehmet Akıf

doi:10.1097/scs.0b013e31824e2c08

Cited by 46 publications

(44 citation statements)

References 15 publications

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“…[7,9] It has been reported in recent studies that MPV increases in obstructive septal deviation and nasal polyps in severe adult OSAS. [6,11,12] The ratio of MPV to platelet count (MPV/PC) is a current reliable marker just like MPV. Higher MPV/PC ratio is associated with myocardial infarction, anemia, deep vein thrombosis, infective endocarditis and hepatocellular carcinoma.…”

mentioning

confidence: 99%

Evaluation of mean platelet volume and its ratio over platelet count in children with obstructive sleep apnea syndrome

Soyalıç

Somuk²,

Doğru³

et al. 2015

Kulak Burun Bogaz Ihtis Derg

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Evaluation of mean platelet volume and its ratio over platelet count in children with obstructive sleep apnea syndromeTıkayıcı uyku apne sendromu olan çocuklarda ortalama trombosit hacmi ve ortalama trombosit hacminin trombosit sayısına oranının değerlendirilmesi ABSTRACTObjectives: This study aims to determine the association between obstructive sleep apnea syndrome (OSAS) caused by adenotonsillar hypertrophy and mean platelet volume (MPV) and MPV/platelet count ratio in children, and to evaluate the impact of adenotonsillectomy on these two parameters. Patients and Methods:This prospective study consisted of 73 child patients (38 boys, 35 girls; mean age 8.6±3.3 years, range 2 to 17 years) with chronic adenotonsillar hypertrophy who applied to Gaziosmanpaşa University Faculty of Medicine, Ear, Nose and Throat policlinics due to witnessed apnea and snoring in January 2011 and January 2013. Also, 56 age and sex matched pediatric patients (28 boys, 26 girls; mean age 8.0±3.2 years; range 3 to 13 years) who admitted to our clinic due to reasons besides OSAS were included in the study as control group. Preoperative and postoperative third month hemoglobin, white blood cell, thrombocyte count, and MPV values of the patients were recorded. Results:Although ratio of MPV/platelet count was higher in patient group than in control group, the difference was not statistically significant. Mean platelet volume level was 7.68±1.07 fL in patient group and 7.21±0.84 fL in control group. Preoperative MPV level in patient group was significantly higher than that in control group (p<0.05). A statistically significant decrease was detected in postoperative third month MPV level and platelet count compared with preoperative MPV and platelet count (7.68±1.07 fL and 7.17±0.97 fL, respectively; p<0.05). Conclusion:High MPV and MPV/platelet count in children with adenotonsillar hypertrophy may be an important risk factor for cardiopulmonary and cerebrovascular morbidities which may develop both in childhood and in adulthood. Adenotonsillectomy may reduce this risk significantly.Keywords: Adenotonsillectomy; mean platelet volume; pediatric obstructive sleep apnea. ÖZAmaç: Bu çalışmada çocuklarda adenotonsiller hipertrofinin neden olduğu tıkayıcı uyku apne sendromu (TUAS) ile ortalama trombosit hacmi (OTH) ve OTH/trombosit sayısı oranı arasındaki ilişki belirlendi ve adenotonsillektominin bu iki parametre üzerindeki etkisi değerlendirildi. Hastalar ve Yöntemler: Bu prospektif çalışmaya Ocak 2011 -Ocak 2013 tarihleri arasında Gaziosmanpaşa Üniversitesi Tıp Fakültesi HastanesiKulak Burun Boğaz Polikliniği'ne tanıklı apne ve horlama nedeni ile başvuran, kronik adenotonsiller hipertrofisi olan 73 çocuk hasta (38 erkek, 35 kız; ort. yaş 8.6±3.3 yıl; dağılım 2-17 yıl) dahil edildi. Ayrıca kliniğimize TUAS dışı nedenlerle başvuran, yaş ve cinsiyet uyumlu 56 çocuk hasta (28 erkek, 26 kız; ort. yaş 8.0±3.2 yıl; dağılım 3-13 yıl) kontrol grubu olarak çalışmaya alındı. Hastaların ameliyat öncesinde ve ameliyat sonrası üçüncü ayda hemoglobin, beyaz...

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mentioning

confidence: 99%

Evaluation of mean platelet volume and its ratio over platelet count in children with obstructive sleep apnea syndrome

Soyalıç

Somuk²,

Doğru³

et al. 2015

Kulak Burun Bogaz Ihtis Derg

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“…MPV level is showed to be higher in patients with pulmonary hypertension [21]. MPV shows platelet activity and large platelets are more active and have more prothrombotic potential [9].…”

Section: Discussionmentioning

confidence: 99%

“…Varol et al [24] revealed that six months of CPAP therapy caused significant reductions in median MPV values in adult patients with severe OSA. Sagit et al [9] found that septoplasty has a curative effect for hypercoagulopathy with reducing MPV values. Kucur et al [25] found that MPV values were found to be higher in children with AH than controls and there was a significant reduction in MPV levels after adenoidectomy.…”

Section: Discussionmentioning

confidence: 99%

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MPV Values in Children with Adenoid Hy-pertrophy and Correlation with Adenoid Size

Özkan¹

2016

OALib

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Background: Adenoid hypertrophy (AH) leads to chronic upper airway obstruction. Upper airway obstruction may cause pulmonary hypertension and right ventricle dysfunction. Mean platelet volume (MPV) may be used as a marker of platelet activation and it is shown that MPV is related to cardiovascular disorders. We investigated in our study if MPV is correlated with adenoid size and can be used as an indicator of obstruction due to adenoid hypertrophy. Methods: 95 children with AH and 99 healthy controls were enrolled in the study. White blood cell, hemoglobin, platelet, Mean platelet volume (MPV) levels were measured before adenoidectomy. Lateral cephalometric graphs were obtained from all patients to measure adenoid/nasopharynx ratio (A/N). The distance between the outermost point of convexity of adenoid shadow and basiocciput was divided to the distance between sphenobasiocciput and posterior end of the hard palate. A/N ratio and MPV levels have been correlated by using Pearson correlation test. Results: There were 45 male and 50 female patients between the ages of 2 and 14 years (mean age: 6.47 ± 2.44). There were no significant differences between children with AH and controls regarding white blood cell, hemoglobin, platelet, MPV and A/N ratio. We didn't detect any correlation between MPV levels and A/N ratio. Conclusion: MPV level was in normal limits in AH children and there was no significant relation between MPV and adenoid severity.

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“…In literature, increasing MPV levels have been associated with the prognosis of some diseases including such as hypertension, unstable angina pectoralis, neurological diseases, autoimmune diseases and obstructive sleep apnea. [8][9][10][11][12][13][14][15] MPV may be used as a marker that indicates chronic intermittent hypoxia. In the study of Somuk et al 16 reported that MPV parameter was found high in the children with chronic effusion otitis media.…”

Section: Introductionmentioning

confidence: 99%

The Relationship Between the Degree of the Mastoid Pneumatization and Mean Platelet Volume

Yeğin¹,

Çelik²,

Şimşek³

et al. 2016

Otolaryngol Open J

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Objectives: To explore the relationships between mean platelet volume (MPV) values and the degree of the mastoid pneumatization. Study Design: A retrospective clinical chart review. Methods: In total, 189 patients (130 females and 59 males; average age, 36.50±15.62 years; age range: 18-65 years) were included in the study. The patients were divided into three groups in terms of the degree of the mastoid pneumatization. The mastoid pneumatization was measured between 0 and 5 cm 3 for group A, between 5 and 10 cm 3 for group B and 10 cm 3 and above for group C, respectively. The MPV values of each groups were compared.

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Impact of Septoplasty on Mean Platelet Volume Levels in Patients With Marked Nasal Septal Deviation

Cited by 46 publications

References 15 publications

Evaluation of mean platelet volume and its ratio over platelet count in children with obstructive sleep apnea syndrome

Evaluation of mean platelet volume and its ratio over platelet count in children with obstructive sleep apnea syndrome

MPV Values in Children with Adenoid Hy-pertrophy and Correlation with Adenoid Size

The Relationship Between the Degree of the Mastoid Pneumatization and Mean Platelet Volume

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