Impact of sarcopenia and its diagnostic criteria on hospitalization and mortality in chronic hemodialysis patients: A 3-year longitudinal study

Lin, Yu‐Li; Liou, Hung-Hsiang; Wang, Chih‐Hsien; Lai, Yu‐Hsien; Kuo, Chiu‐Huang; Chen, Shuyuan; Hsu, Bang‐Gee

doi:10.1016/j.jfma.2019.10.020

Cited by 40 publications

(39 citation statements)

References 29 publications

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“…Porém em alguns estudos, observaram que o IMC apresentou uma correlação fraca com a FPP, podendo ser justificado pela incapacidade desta medida diferenciar massa magra de massa adiposa (LEAL et al, 2011;PINTO et al, 2015;CALLEGARI et al, 2018;HERNANDEZ et al, 2020). É importante ressaltar que outras patologias podem interferir na FPP, como o diabetes e a hipertensão, no estudo de Hernandez et al (2020) os pesquisadores fazem essa correlação, devido algumas doenças terem uma ação catabólica sobre a massa muscular, assim corroboram com essa afirmação os trabalhos de (ISOYAMA et al, 2014;PINTO et al, 2015;HASHEMINEJAD et al, 2016;CALLEGARI et al, 2018;LIN et al, 2020). Os estudos mostram que independente do sexo e idade, pacientes diabéticos apresentaram menor valores na FPP comparado com pacientes não diabéticos.…”

Section: Discussionunclassified

“…Brazilian Journal of Development, Curitiba, v.7, n.4, p. 38106-38124 apr 2021 Em relação aos parâmetros laboratoriais junto a aplicabilidade da FPP e seus critérios avaliativos, mostrou que valores inadequados de hemoglobina, taxa de filtração glomerular e creatinina sérica foram correlacionadas a baixa força muscular, na pesquisa 68% dos analisados apresentaram hemoglobina baixa, podendo resultar num impacto negativo na força muscular desses pacientes (HERNANDEZ et al, 2020). Outros estudos também fizeram a correlação de parâmetros laboratoriais e FPP no desfecho da perda de massa magra, Isoyama et al (2014) e Lin et al (2020) observaram que os valores de creatinina sérica são menores em pacientes com baixa força muscular em comparação aos pacientes com força muscular normal. No trabalho de Lin et al (2020) ainda observou que a creatinina sérica foi menor também em pacientes com baixa quantidade de massa muscular e baixa velocidade de marcha, considerando que a creatinina se mostrou um preditor independente, sugerindo o marcador confiável para avaliação de perda muscular nessa população em hemodiálise.…”

Section: Discussionunclassified

“…A albumina sérica, é um marcador nutricional bastante utilizado nos parâmetros da desnutrição e em relação aos pacientes com DRC, nos estudos de Callegari et al (2018) e Lin et al (2020) observaram a relação com menor valores de albumina sérica e baixa FPP. Porém os valores da albumina sérica podem ser influenciados pelo estado de hidratação do paciente e inflamação, diferentemente da FPP, o que é sugerido nos estudos de (LEAL et al, 2011;SOSTISSO et al, 2020).…”

Section: Discussionunclassified

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Viabilidade da utilização da força de preensão palmar para avaliação de perda de massa magra em pacientes dialíticos / Feasibility of using the palmar pressure force for assessment of loss of lean mass in dialytic patients

Jalesky¹,

Baumel²,

Belo³

et al. 2021

BJDV

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Introdução: O acompanhamento periódico do estado nutricional do paciente com doença renal crônica, através da avaliação nutricional se torna fundamental para um diagnóstico precoce, prevenção e tratamento da desnutrição. Esse estudo objetivou compreender a viabilidade da utilização do teste força de preensão palmar (FPP) na avaliação da perda da massa e força muscular em pacientes que realizam hemodiálise. Métodos: Refere-se a um estudo de revisão integrativa, onde foram pesquisados os descritores no MESH: Handgrip strength and hemodialysis e DECS: Força de preensão palmar e hemodiálise,

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Section: Discussionunclassified

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Viabilidade da utilização da força de preensão palmar para avaliação de perda de massa magra em pacientes dialíticos / Feasibility of using the palmar pressure force for assessment of loss of lean mass in dialytic patients

Jalesky¹,

Baumel²,

Belo³

et al. 2021

BJDV

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“…Sarcopenia reduces the physical function of MHD patients, impairs their ability to conduct daily living activities, and leads to a decline in patients' quality of life. It also increases the risk of hospitalization and hospitalization costs, and it is an independent predictor of mortality in MHD patients [4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Characterization of the gut microbiota in hemodialysis patients with sarcopenia

et al. 2021

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Purpose Maintenance hemodialysis (MHD) patients are at high risk of sarcopenia. Gut microbiota affects host metabolic and may act in the occurrence of sarcopenia importantly. This study aimed to study the characterization of the gut microbiota in MHD patients with sarcopenia, and to further reveal the complex pathophysiology of sarcopenia in MHD patients. Methods Fecal samples and clinical data were collected from 30 MHD patients with sarcopenia, and 30 age-and-sex-matched MHD patients without sarcopenia in 1 general hospital of Jiangsu Province from December 2020 to March 2021. 16S rRNA sequencing technology was used to analyze the genetic sequence of the gut microbiota for evaluation of the diversity, species composition, and differential microbiota of the two groups. Results Compared to MHD patients without sarcopenia, the ACE index of patients with sarcopenia was lower (P = 0.014), and there was a structural difference in the β-diversity between the two groups (P = 0.001). At the genus level, the relative abundance of Tyzzerella_4 in the sarcopenia group was significantly higher than in the non-sarcopenia group (P = 0.039), and the relative abundance of Megamonas (P = 0.004), Coprococcus_2 (P = 0.038), and uncultured_bacterium_f_Muribaculaceae (P = 0.040) decreased significantly. Conclusion The diversity and structure of the gut microbiota of MHD patients with sarcopenia were altered. The occurrence of sarcopenia in MHD patients may be influenced by gut microbiota.

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“…Estudos demonstraram que a FPP é uma medida de forte influência relacionada à capacidade e função física (GRAY; GLENN; BINNS, 2016). Os novos "guidelines" sugerem sua inclusão como variável para avaliação da função muscular e preditor de sarcopenia (CRUZ-JENTOFT et al, 2019), bem como morbimortalidade (Lin et al, 2020).…”

Section: Força De Preensão Palmarunclassified

Aplicação de métodos de imagem, bioelétricos, antropométricos e funcionais para avaliação de composição corporal e estado nutricional na doença renal crônica

Bellafronte¹

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women 75% and 97% and in men, 75% and 95%. The prevalence of sarcopenia in total sample was 7% (FNIH) and 5% (EWGSOP2). Low muscle mass was present in 39% (FNIH) and 36% (EWGSOP2). Dynapenia affected 10% of the participants (FNIH and EWGSOP2). Sarcopenic patients presented lower body adiposity by EWGSOP2 criteria and higher adiposity by FNIH. The impact of fatigue on daily activities was significantly different in HD patients and in individuals classified as presenting low HGS and sarcopenia. Prevalence of muscle depletion evaluated by FFMI, AFFMI and HGS varied from 11 to 50%, higher for low muscle mass. Prevalence of obesity evaluated by BMI, FMI, %FM and WC varied from 26 to 62%, higher for WC and %FM. Prevalence of sarcopenic obesity varied from 2 to 23%. Women were more affected by sarcopenic obesity. Muscle depletion and sarcopenic obesity where more prevalent among HD and obesity among NDD and KTx patients. The agreement was poor among muscle mass and strength criteria; substantial between FMI, BMI, and %FM and fair among WC and the others; for sarcopenic obesity, varied from almost perfect to poor. Conclusions: For body composition evaluation in patients with CKD, BIS applied using the whole body protocol in normal hydration patients with CKD is as reliable as DXA. However, BIS must be used with caution in overhydration patients with ECW/ICW ≥ 0.7250. The newly developed equations are indicated for greater precision. AFFM by BIS alone and in addition to HGS, FMI by BIS alone and in addition to AFFM, with the proposed cut-offs, are recommended as altenative tools for diagnosis of low muscle mass, sarcopenia, obesity and sarcopenic obesity, respectively. These alternative measurements need external validation before routine use in clinical practice. Our results suggest that in adult CKD patients, sarcopenia and low muscle mass prevalence varies according to the diagnostic criteria and are common conditions. Body adiposity association with sarcopenia depends on the criteria used to define this syndrome with FNIH criteria detecting higher adiposity in individuals with sarcopenia.Fatigue pictogram could be applied for screening patients at risk of decreased functional capacity. In addition, significant differences were found among low muscle mass vs low muscle strength and high total body fat vs high visceral fat diagnostic criteria that are added in sarcopenic obesity diagnosis.

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Impact of sarcopenia and its diagnostic criteria on hospitalization and mortality in chronic hemodialysis patients: A 3-year longitudinal study

Cited by 40 publications

References 29 publications

Viabilidade da utilização da força de preensão palmar para avaliação de perda de massa magra em pacientes dialíticos / Feasibility of using the palmar pressure force for assessment of loss of lean mass in dialytic patients

Viabilidade da utilização da força de preensão palmar para avaliação de perda de massa magra em pacientes dialíticos / Feasibility of using the palmar pressure force for assessment of loss of lean mass in dialytic patients

Characterization of the gut microbiota in hemodialysis patients with sarcopenia

Aplicação de métodos de imagem, bioelétricos, antropométricos e funcionais para avaliação de composição corporal e estado nutricional na doença renal crônica

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