Impact of Restrictive (Sleeve Gastrectomy) vs Hybrid Bariatric Surgery (Roux-en-Y Gastric Bypass) on Lipid Profile

Benaiges, David; Flores-Le-Roux, Juana A.; Pedro‐Botet, Juan; Ramón, José́; Parri, A.; Villatoro, Montserrat; Carrera, María; Pera, Manuel; Sagarra, Enric Ballesteros i; Grande, Luís; Goday, Albert

doi:10.1007/s11695-012-0662-8

Cited by 93 publications

(55 citation statements)

References 38 publications

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“…These findings can be explained based on the structural remolding of the gastric musculature. These findings were consistent with previously reported findings (Aarts et al, 2011;Benaiges et al, 2012). Clearly the amount of dietary intake induct stretching of the gastric wall which in turn becomes more effective during the second year after more tissue of gastric remodeling had been established.…”

Section: Discussion:-supporting

confidence: 93%

Weight Regain After Sleeve Gastrectomy.

Akilan¹

2017

IJAR

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Background: Gastric size determines the amount of dietary intake which in turn determines energy intake. Body weight loss depends on negative energy balance. Objectives:The primary purpose of the present study was to assess body weight loss for 36 months in patients who underwent gastric sleeve surgery. A secondary purpose was to examine the impact of gender and age on weight changes before and after surgery. Methods: A total of 309 patients were enrolled sequentially. Age, body weight, gender, BMI, and comorbidity were assessed before and after gastric sleeve surgery for 36 months. Results: Results showed that body weight before and after surgery was influenced by both age category and gender. It was also noted that the rate of body weight reduction was faster during the 1 st 12 months compared to the 2 nd 12 months. Conclusions:Based on the results of the present study, it can be concluded that prior and post gastric sleeve surgery body weight is influenced by age and gender. The rate of weight reduction after gastric sleeve surgery is faster during the first 12 months, compared to the second 12 months. Gastric sleeve affected body loss and that can be considered as effective treatment for obesity and obesity related diseases.

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Section: Discussion:-supporting

confidence: 93%

Weight Regain After Sleeve Gastrectomy.

Akilan¹

2017

IJAR

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“…These findings are in keeping with other studies showing that mixed malabsorptive and restrictive surgery (GBP) is more effective than restrictive surgery (SG) in reducing cholesterol levels 37,38 and more specifically that TC and LDL-C are significantly reduced 12 months after GBP but not after SG. 39 In malabsorptive surgery, it has been shown that intestinal cholesterol absorption decreases leading to decreased plasma TC and LDL-C concentrations, accompanied by enhanced hepatic cholesterol synthesis and catabolism. 40 In the present study, the greater reduction in total apoB in GBP compared with SG could be explained by a specific reduction of LDL particle numbers in GBP.…”

Section: Discussionmentioning

confidence: 99%

Impact of bariatric surgery on apolipoprotein C-III levels and lipoprotein distribution in obese human subjects

Maraninchi¹,

Padilla²,

Béliard

et al. 2017

Journal of Clinical Lipidology

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BACKGROUND: Elevated apolipoprotein C-III (apoC-III) has been postulated to contribute to the atherogenic dyslipidemia seen in obesity and insulin-resistant states, mainly by impairing plasma triglyceride-rich lipoprotein (TRL) metabolism. Bariatric surgery is associated with improvements of several obesity-associated metabolic abnormalities, including a reduction in plasma triglycerides (TGs) and an increase in plasma high-density lipoprotein cholesterol (HDL-C).OBJECTIVES: We investigated the specific effect of bariatric surgery on apoC-III concentrations in plasma, non-HDL, and HDL fractions in relation to lipid profile parameters evolution.METHODS: A total of 132 obese subjects undergoing bariatric surgery, gastric bypass (n 5 61) or sleeve gastrectomy (n 5 71), were studied 1 month before surgery and 6 and 12 months after surgery.RESULTS: Plasma apoC-III, non-HDL-apoC-III, and HDL-apoC-III concentrations were markedly reduced after surgery and strongly associated with reduction in plasma TG. This decrease was E-mail address: rvalero@mail.ap-hm.fr accompanied by a redistribution of apoC-III from TRL to HDL fractions. In multivariate analysis, plasma apoC-III was the strongest predictor of TG reduction after surgery, and the increase of HDL-C was positively associated with plasma adiponectin and negatively with body mass index.CONCLUSION: Marked reduction of apoC-III and changes in its distribution between TRL and HDL consistent with a better lipid profile are achieved in obese patients after bariatric surgery. These apoC-III beneficial modifications may have implications in dyslipidemia improvement and contribute to cardiovascular risk reduction after surgery.

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“…The results obtained for the two different types of surgeries were not very different from one another, although it is known that the sleeve type of surgery is considered a better option for the management of diabetes; it has been shown that there are particular benefits in terms of the resolution of type II diabetes with this type of surgery. 19 This type of surgery has also been shown to produce improvement in the patients' total cholesterol and their LDL, although the sleeve type of surgery improves the patients' triglycerides and increases their levels of HDL. 19,20 Hepatic steatosis is a disease frequently found in patients with morbid obesity and is one of the main causes of chronic liver disease, such as steatohepatitis, chronic inflammation, cirrhosis, and eventually hepatocellular carcinoma.…”

Section: Discussionmentioning

confidence: 99%

“…19 This type of surgery has also been shown to produce improvement in the patients' total cholesterol and their LDL, although the sleeve type of surgery improves the patients' triglycerides and increases their levels of HDL. 19,20 Hepatic steatosis is a disease frequently found in patients with morbid obesity and is one of the main causes of chronic liver disease, such as steatohepatitis, chronic inflammation, cirrhosis, and eventually hepatocellular carcinoma. Hepatic steatosis makes up part of the metabolic diseases that are related to insulin resistance.…”

Section: Discussionmentioning

confidence: 99%

Obesity-related Metabolic Comorbidities Remission in Postbariatric Surgery Patients

Dorado¹,

López²,

Martin³

2017

WJOLS

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Impact of Restrictive (Sleeve Gastrectomy) vs Hybrid Bariatric Surgery (Roux-en-Y Gastric Bypass) on Lipid Profile

Abstract: LRYGB produces an overall improvement in lipid profile, with a clear benefit in all lipid fractions. Although LSG does not alter LDL cholesterol levels, its effect on HDL cholesterol is comparable to or greater than that obtained with malabsorptive techniques.

Cited by 93 publications

References 38 publications

Weight Regain After Sleeve Gastrectomy.

Weight Regain After Sleeve Gastrectomy.

Impact of bariatric surgery on apolipoprotein C-III levels and lipoprotein distribution in obese human subjects

Obesity-related Metabolic Comorbidities Remission in Postbariatric Surgery Patients

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