Impact of Replacing the Pooled Cohort Equation With Other Cardiovascular Disease Risk Scores on Atherosclerotic Cardiovascular Disease Risk Assessment (from the Multi-Ethnic Study of Atherosclerosis [MESA])

Do the 2017 blood pressure cut-offs improve 10-year cardiovascular disease mortality risk prediction?

“…Firstly, we could notice the observed versus predicted ratios have still deviated from the ideal curve in high-risk population, which may be due to the small population size. Secondly, although SCORE model demonstrated acceptable prediction ability in US population [9,20], whether the modified model could be widely used in the general US population is still debatable.…”

Assessing the Relationship between Atherosclerotic Cardiovascular Disease Risk Score and Carotid Artery Imaging Findings

“…The 10-year ASCVD risk score had the best net benefit compared to the modified Framingham risk score. 17 We found that patients with higher 10-year ASCVD risk score overall had more stenosis, thicker artery walls, more soft plaques, and more ulcerations. Calcified plaque was the only imaging feature that was frequently observed in patients with both low and high 10-year ASCVD risk score.…”

“…The goal of our study was to determine whether patients with a higher 10‐year ASCVD risk score have more advanced imaging features of carotid artery atherosclerosis. The 10‐year ASCVD risk score had the best net benefit compared to the modified Framingham risk score . We found that patients with higher 10‐year ASCVD risk score overall had more stenosis, thicker artery walls, more soft plaques, and more ulcerations.…”

Prognostic value of exercise capacity among patients with treated depression: The Henry Ford Exercise Testing (FIT) Project

“…Selection of variables for entry consideration was based on expertise of the investigators, clinical judgment, and the results of previous publications. 13,20 In addition, effect modification on the results was assessed for the covariates of age, sex, and race. The P values for effect of modification were determined via Wald tests and were more often hypertensive (86.4% vs 50.6%, respectively; P < 0.001), had DM (38.0% vs 8.9%, respectively; P < 0.001) and dyslipidemias (54.2% vs 44.6%, respectively; P < 0.001), were obese (36.1% vs 11.0%, respectively; P < 0.001), and had more often a prior revascularization procedure (either percutaneous coronary intervention [7.0% vs 2.5%] or coronary artery bypass grafting [6.3% vs 0.8%], P < 0.001; Table 1 Better survival and fewer events (ACM and nonfatal MI) developed was associated with higher exercise capacity achieved.…”

“…The secondary analysis was used to assess the association between METs achieved (as METs groups and per 1‐MET increase) and nonfatal MI after adjusting for the same models. Selection of variables for entry consideration was based on expertise of the investigators, clinical judgment, and the results of previous publications . In addition, effect modification on the results was assessed for the covariates of age, sex, and race.…”