Impact of PTSD and Obstructive Sleep Apnea on Cognition in Older Adult Veterans

Noland, Madeline; Paolillo, Emily W; Noda, Art; Lazzeroni, Laura C.; Holty, Jon-Erik C; Kuschner, Ware G.; Yesavage, Jerome A.; Kinoshita, Lisa M.

doi:10.1177/08919887221149132

Cited by 2 publications

(2 citation statements)

References 71 publications

(107 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Veterans with PTSD and comorbid obesity display increased likelihood for mental and physical health problems such as MDD, suicidality, nicotine dependence, diabetes, hypertension, insomnia, and migraine relative to veterans with solo PTSD or obesity [29]. PTSD is also a significant predictor of poor attention and processing speed in older adult male veterans with cognitive deficits [30]. This is probably because of its cardiovascular and metabolic consequences.…”

Section: Introductionmentioning

confidence: 99%

Cardiometabolic Morbidity (Hypertension and Obesity) in PTSD: Treatment Implications for the Predictive Validity of Two Structures of the Impact of Event Scale-Revised

Ali,

Al-Dossary,

Laranjeira

et al. 2023

Preprint

View full text Add to dashboard Cite

Posttraumatic stress disorder (PTSD) and/or specific PTSD symptoms may evoke disordered eating and unhealthy lifestyles, resulting in adverse cardiometabolic events (e.g., hypertension and obesity) in certain groups, which may implicate the treatment of this complex condition. The diagnostic criteria of PTSD have lately expanded beyond the three common symptoms (intrusion, avoidance, and hyperarousal). Simultaneously, four-, five-, and six-dimensional structures of the Impact of Event Scale-Revised (IES-R), a popular PTSD measure, seem to be more robust than the original three-dimension structure. Within the context of COVID-19, this instrumental study used a convenience sample of 58 dental healthcare workers (HCWs) from Russia (mean age = 44.1±12.2 years, 82.8% females) to examine the criterion and predictive validity of two IES-R structures: the IES-R3 and the IES-R6 (with the added symptoms of numbing, sleep disturbance, and irritability). The subscales of the two IES-R structures expressed good internal consistency, strong correlations with the PTSD Symptom Scale (PSS), hypertension diagnosis, and high body mass index (BMI). In receiver-operating characteristic (ROC) curve analysis, all IES-R models perfectly predicted the PSS (all area under the curve (AUC) >0.9, p values <0.001). The IES-R, both hyperarousal subscales, and the IES-R3 intrusion subscale significantly predicted high BMI. Both avoidance subscales and the IES-R3 intrusion subscale, not the IES-R, significantly predicted hypertension. In conclusion, both IES-R structures can reliably measure PTSD symptoms. The IES-R, hyperarousal, and intrusion may be credible criterion variables for predicting high BMI within PTSD while the intrusion and avoidance subscales may reflect the cardiovascular consequences associated with PTSD more reliably than the IES-R itself. The IES-R subscales may predict cardiometabolic adversities in PTSD, signifying a need for proper assessment of lifestyle and the application of dietary and exercise interventions in order to lower physical morbidity in PTSD. Replicating the study in larger samples, which comprise different physical and mental conditions from heterogenous cultural contexts is pivotal to validate the results (e.g., in specific groups such as those with confirmed traumatic exposure and comorbid mood dysfunction).

show abstract

Section: Introductionmentioning

confidence: 99%

Cardiometabolic Morbidity (Hypertension and Obesity) in PTSD: Treatment Implications for the Predictive Validity of Two Structures of the Impact of Event Scale-Revised

Ali,

Al-Dossary,

Laranjeira

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…Veterans with PTSD and comorbid obesity display increased likelihood of mental and physical health problems such as MDD, suicidality, nicotine dependence, diabetes, hypertension, insomnia, and migraine relative to veterans with solo PTSD or obesity [24]. PTSD is also a signi cant predictor of poor attention and processing speed in older adult male veterans with cognitive de cits [25]. This is probably because of its cardiovascular and metabolic consequences.…”

Section: Introductionmentioning

confidence: 99%

Predictive validity of the six-dimension structure of the Impact of Event Scale- Revised for PTSD and related-cardiometabolic consequences (hypertension and obesity) among dental healthcare workers during COVID-19

Ali

Al-Dossary

Aljubilah

et al. 2023

Preprint

View full text Add to dashboard Cite

The diagnostic criteria of posttraumatic stress disorder (PTSD) have lately expanded beyond the three common symptoms (intrusion, avoidance, and hyperarousal). Simultaneously, four-, five-, and six-dimensional structures of the Impact of Event Scale-Revised (IES-R), a popular PTSD measure, seem to be more robust than the original three-dimension structure. PTSD and/or specific PTSD symptoms may also evoke adverse cardiometabolic events (e.g., hypertension and obesity) in certain groups. Employing a convenience sample of 58 dental healthcare workers (HCWs) from Russia (mean age = 44.1 ± 12.2 years, 82.8% females), this instrumental study examined the criterion and predictive validity of two IES-R structures: the IES-R3 and the IES-R6 (with added symptoms of numbing, sleep disturbance, and irritability). The subscales of the two IES-R structures expressed good internal consistency, strong correlations with the PTSD Symptom Scale (PSS), hypertension diagnosis, and high body mass index (BMI). In receiver-operating characteristic (ROC) curve analysis, all IES-R models perfectly predicted the PSS (all area under the curve (AUC) values > 0.9, p values < 0.001). The IES-R, both hyperarousal subscales, and the IES-R3 intrusion significantly predicted high BMI. The IES-R did not predict hypertension, but the avoidance subscales and the IES-R3 intrusion significantly predicted it. In conclusion, both IES-R structures can reliably measure PTSD symptoms. The IES-R, hyperarousal, and intrusion may be credible criterion variables for predicting high BMI within PTSD while the intrusion and avoidance subscales may more reliably reflect the cardiovascular consequences of the stress reaction associated with PTSD than the IES-R itself. It is pivotal to verify the results in specific groups (e.g., those with confirmed traumatic exposure and comorbid mood dysfunction). Replication of the study in larger samples, which comprise different physical and metal conditions from heterogenous cultural contexts is necessary.

show abstract

Impact of PTSD and Obstructive Sleep Apnea on Cognition in Older Adult Veterans

Cited by 2 publications

References 71 publications

Cardiometabolic Morbidity (Hypertension and Obesity) in PTSD: Treatment Implications for the Predictive Validity of Two Structures of the Impact of Event Scale-Revised

Cardiometabolic Morbidity (Hypertension and Obesity) in PTSD: Treatment Implications for the Predictive Validity of Two Structures of the Impact of Event Scale-Revised

Predictive validity of the six-dimension structure of the Impact of Event Scale- Revised for PTSD and related-cardiometabolic consequences (hypertension and obesity) among dental healthcare workers during COVID-19

Contact Info

Product

Resources

About