Impact of probe-induced abdominal compression on two-dimensional shear wave elastography measurement of split liver transplants in children

Groth, Michael; Fischer, Lutz; Herden, Uta; Brinkert, Florian; Beime, Jan; Deindl, Philipp; Adam, Gerhard; Herrmann, Jochen

doi:10.1055/a-2049-9369

Cited by 3 publications

(1 citation statement)

References 28 publications

(63 reference statements)

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“…Participants were placed in the supine position with a pillow placed under their knees to minimize lumbar lordosis and received instructions to relax their neck muscles during the procedure (in order to avoid muscle stiffness changes due to muscle contractions [ 27 ]). Then, the transducer was placed in the supraclavicular region beside the cricoid cartilage, using enough US gel for avoiding probe compression, as this could influence SWE measurements [ 28 ]. A lateral gliding was performed until placing the carotid artery on the lateral extreme of the image.…”

Section: Methodsmentioning

confidence: 99%

Body Composition and Demographic Features Do Not Affect the Diagnostic Accuracy of Shear Wave Elastography

Varol,

Valera-Calero,

Fernández-de-las-Peñas

et al. 2023

Bioengineering

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Shear-wave elastography (SWE) is an imaging method that can be used to estimate shear wave speed and the Young’s modulus based on the measured shear wave speed under certain conditions. Up to date, no research has analyzed whether body composition factors contribute to ultrasound attenuation, refraction, reflection, and, consequently, SWE measurement errors. Therefore, this study aimed to analyze the association between demographic and body composition features with SWE errors for assessing the anterior scalene stiffness (which is a key structure in patients with neck pain and nerve compressive syndromes). Demographic (sex, age, height, weight, and body mass index), body composition (water volume, fat mass, and lean mass), and anterior scalene muscle stiffness (Young’s modulus and shear wave speed) data were collected from a sample of asymptomatic subjects. After calculating the absolute SWE differences between trials and the reliability estimates, a correlation matrix was generated to quantify the association among all the variables. A total of 34 asymptomatic subjects (24 males) were included in the analyses. Test–retest reliability was excellent for assessing the Young’s modulus and shear wave velocity (ICC = 0.912 and 0.923, respectively). No significant associations were found between age, height, weight, body mass index, body fat, lean mass, or water volume with SWE errors (p > 0.05). However, the Young’s modulus error was associated with the stiffness properties (p < 0.01), whereas shear wave speed was associated with none of them (all, p > 0.05). A detailed procedure can reliably assess the AS muscle stiffness. None of the sociodemographic or body composition features assessed were correlated with SWE errors. However, baseline stiffness seems to be associated with Young’s modulus error.

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Section: Methodsmentioning

confidence: 99%

Body Composition and Demographic Features Do Not Affect the Diagnostic Accuracy of Shear Wave Elastography

Varol,

Valera-Calero,

Fernández-de-las-Peñas

et al. 2023

Bioengineering

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Altered probe pressure and body position increase diagnostic accuracy for men and women in detecting hepatic steatosis using quantitative ultrasound

Byenfeldt,

Kihlberg,

Nasr

et al. 2024

Eur Radiol

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Objectives To evaluate the diagnostic performance of ultrasound guided attenuation parameter (UGAP) for evaluating liver fat content with different probe forces and body positions, in relation to sex, and compared with proton density fat fraction (PDFF). Methods We prospectively enrolled a metabolic dysfunction-associated steatotic liver disease (MASLD) cohort that underwent UGAP and PDFF in the autumn of 2022. Mean UGAP values were obtained in supine and 30° left decubitus body position with normal 4 N and increased 30 N probe force. The diagnostic performance was evaluated by the area under the receiver operating characteristic curve (AUC). Results Among 60 individuals (mean age 52.9 years, SD 12.9; 30 men), we found the best diagnostic performance with increased probe force in 30° left decubitus position (AUC 0.90; 95% CI 0.82–0.98) with a cut-off of 0.58 dB/cm/MHz. For men, the best performance was in supine (AUC 0.91; 95% CI 0.81–1.00) with a cut-off of 0.60 dB/cm/MHz, and for women, 30° left decubitus position (AUC 0.93; 95% CI 0.83–1.00), with a cut-off 0.56 dB/cm/MHz, and increased 30 N probe force for both genders. No difference was in the mean UGAP value when altering body position. UGAP showed good to excellent intra-reproducibility (Intra-class correlation 0.872; 95% CI 0.794–0.921). Conclusion UGAP provides excellent diagnostic performance to detect liver fat content in metabolic dysfunction-associated steatotic liver diseases, with good to excellent intra-reproducibility. Regardless of sex, the highest diagnostic accuracy is achieved with increased probe force with men in supine and women in 30° left decubitus position, yielding different cut-offs. Clinical relevance statement The ultrasound method ultrasound-guided attenuation parameter shows excellent diagnostic accuracy and performs with good to excellent reproducibility. There is a possibility to alter body position and increase probe pressure, and different performances for men and women should be considered for the highest accuracy. Key Points • There is a possibility to alter body position when performing the ultrasound method ultrasound-guided attenuation parameter. • Increase probe pressure for the highest accuracy. • Different performances for men and women should be considered. Graphical Abstract

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Quantitative Liver Imaging in Children

Yoon,

Kim,

Lim

et al. 2024

Invest Radiol

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In children and adults, quantitative imaging examinations determine the effectiveness of treatment for liver disease. However, pediatric liver disease differs in presentation from liver disease in adults. Children also needed to be followed for a longer period from onset and have less control of their bodies, showing more movement than adults during imaging examinations, which leads to a greater need for sedation. Thus, it is essential to appropriately tailor and accurately perform noninvasive imaging tests in these younger patients. This article is an overview of updated imaging techniques used to assess liver disease quantitatively in children. The common initial imaging study for diffuse liver disease in pediatric patients is ultrasound. In addition to preexisting echo analysis, newly developed attenuation imaging techniques have been introduced to evaluate fatty liver. Ultrasound elastography is also now actively used to evaluate liver conditions, and the broad age spectrum of the pediatric population requires caution to be taken even in the selection of probes. Magnetic resonance imaging (MRI) is another important imaging tool used to evaluate liver disease despite requiring sedation or anesthesia in young children because it allows quantitative analysis with sequences such as fat analysis and MR elastography. In addition to ultrasound and MRI, we review quantitative imaging methods specifically for fatty liver, Wilson disease, biliary atresia, hepatic fibrosis, Fontan-associated liver disease, autoimmune hepatitis, sinusoidal obstruction syndrome, and the transplanted liver. Lastly, concerns such as growth and motion that need to be addressed specifically for children are summarized.

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Impact of probe-induced abdominal compression on two-dimensional shear wave elastography measurement of split liver transplants in children

Cited by 3 publications

References 28 publications

Body Composition and Demographic Features Do Not Affect the Diagnostic Accuracy of Shear Wave Elastography

Body Composition and Demographic Features Do Not Affect the Diagnostic Accuracy of Shear Wave Elastography

Altered probe pressure and body position increase diagnostic accuracy for men and women in detecting hepatic steatosis using quantitative ultrasound

Quantitative Liver Imaging in Children

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