Impact of Prevascularization on Immunological Environment and Early Engraftment in Subcutaneous Islet Transplantation
Kenta Inoguchi,
Takayuki Anazawa,
Nanae Fujimoto
et al.
Abstract:Background.
The utilization of islet-like cells derived from pluripotent stem cells may resolve the scarcity of islet transplantation donors. The subcutaneous space is a promising transplantation site because of its capacity for graft observation and removal, thereby ensuring safety. To guarantee subcutaneous islet transplantation, physicians should ensure ample blood supply. Numerous methodologies, including prevascularization, have been investigated to augment blood flow, but the optimal approach… Show more
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