Impact of post-treatment on the characteristics of electrospun poly (vinyl alcohol)/chitosan nanofibers

Abstract

Abstract. Electrospun nanofibers have many advantages such as high porosity, easy to be fabricated in various size and high ratio of surface area to volume. This paper presents the preparation of electrospun PVA/Chitosan nanofibers and more specifically focuses on the effect of post-treatment on the permeability and morphology of electrospun PVA/chitosan nanofibers. The mixtures of various concentrations of PVA (6,7,8 wt%)and 2 wt%.chitosan solution (with the ratio of 3:1)were used in electrospun with a constant rate of 0.7 ml/hour. The post-treatment was conducted by immersing in a ethanol or glutaraldehyde solution to performed crosslink structure. The electrospun PVA/Chitosan nanofiber was characterized by scanning electron microscopy (SEM) and fourier transform infrared (FTIR) spectroscopy. The results revealed that the viscosity of the mixture solution is directly proportional to its concentration. Increasing the viscosity increased the diameter of fiber but also made the larger beads formation. FTIR measurement exhibited the existence of relevant functional groups of both PVA and chitosan in the composites.The crosslinked structure was found for the electrospun PVA/Chitosan nanofibers treated with glutaraldehyde solution.

Preparation and Characterization of Sodium Alginate Polymeric Scaffold by Electrospinning Method for Skin Tissue Engineering Application

“…Appeared peak at 1088 cm -1 belongs CN group. The appeared sharp peak at 1717 cm -1 is attributed to the carboxylate group [55]. Comparing with the control group, a shoulder appeared before the peak at 1087 cm -1 and expanded the appeared peak.…”

Enzymatic Time-Temperature Indicator Prototype Developed by Immobilizing Laccase on Electrospun Fibers to Predict Lactic Acid Bacterial Growth in Milk during Storage

“…Susanto et al [ 14 ] reported that cross-linking PVA/CS nanofibers with GA resulted in morphological changes to the membrane microstructure, such as an increase in fiber diameter. The addition of GA may produce a more stable membrane because, theoretically, it more efficiently cross-links the free –OH groups of PVA and amine groups of CS to the aldehyde group of GA. Koloti et al [ 23 ] reported that laccase enzymes could be anchored on fibers through the formation of bonds with the abundant peripheral amine groups of CS by using GA as a cross-linker, which resulted in the increased thickness of the laccase-modified membrane surface; this was attributed to the swelling of nanofibers onto which the enzymes were covalently immobilized.…”

“…However, electrospinning of CS has some limitations; for example, creating continuous fiber jets during electrospinning is difficult because of the repulsive forces between ionic groups and the high surface tension of the polymer solution given that CS has high viscosity even at moderate concentrations. To overcome these limitations, CS is commonly blended with other polymers for electrospinning, such as polyvinyl alcohol (PVA) [ 14 ].…”

Overview of Nano-fiber Bundles Fabrication via Electrospinning and Morphology Analysis

“…Additionally, the needle-based approach allows for precise monitoring of the flow rate, minimizes solution waste, and utilizes a small number of jets. Numerous benefits have contributed to the needle-based method's widespread usage [42].…”