Impact of Perfusion Modalities on Cerebral Hemodynamics, Organ Injury, and Clinical Outcomes in Acyanotic and Cyanotic Congenital Heart Surgery Patients
Abstract:Background: Acyanotic and cyanotic congenital heart disease (CHD) patients are known to have distinct operative risk profiles. However, little is known about whether pulsatile and non-pulsatile cardiopulmonary bypass (CPB) have differential effects on cerebral hemodynamics or outcomes in these two patient groups.
Methods: 159 pediatric (age <18 years) cardiac surgery patients were randomized to pulsatile or non-pulsatile CPB. Patients were stratified by type of CHD: acyanotic versus cyanotic. Intraoperative… Show more
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