Impact of patient age on propofol consumption during propofol-remifentanil anaesthesia

Abstract

We conclude that with Narcotrend guidance, mean propofol consumption and recovery times are age dependent. However, as a result of large inter-individual variability, age per se does not allow a prediction of individual propofol need or recovery time.

Patient Sex and its Influence on General Anaesthesia

“…While one study has found women to be more sensitive to the effects of propofol based on lower plasma concentrations required to produce similar bispectral index (BIS) levels 144 , other studies have found no difference 145 or the reverse to be true 146,149 . In the same studies, women required more propofol to achieve the same depth of anaesthesia as monitored by Narcotrend 146,147 . Reduced propofol sensitivity in women is supported by a requirement for more propofol to lose consciousness 5,149,150 and to maintain anaesthesia during surgery 5,149,150 , when adjusted for body weight.…”

Multivariate analysis of factors associated with post-anesthetic times to standing in isoflurane-anesthetized horses: 381 cases

“…The majority of independent variables did not significantly impact the standing time in this group of horses. Gender and age affect time to awakening in people (Kreuer et al 2005;Buchanan et al 2006), but were not shown to be predictors for standing in this groups of horses. Xylazine has been shown to prolong but improve the quality of recoveries in horses (Santos et al 2003).…”

“…The majority of independent variables did not significantly impact the standing time in this group of horses. Gender and age affect time to awakening in people (Kreuer et al. 2005; Buchanan et al.…”

Factors Affecting Successful Localization of the Central Sulcus Using the Somatosensory Evoked Potential Phase Reversal Technique

“…25 Age has been previously shown to influence intraoperative electrophysiology, but primarily through alteration of anesthetic pharmacokinetics and cortical suppression. 13,[26][27][28][29][30] In our study, the age of the patient did not have any demonstrable effect on the rate of CS localization, quite possibly because our patient population (age range, 7-78 years) did not include very young children or octogenarians.…”