Impact of oral health status on healthy life expectancy in community-dwelling population: The AGES Project cohort study

Effects of Scaffold Shape on Bone Regeneration: Tiny Shape Differences Affect the Entire System

“…As the global population is aging rapidly, healthy life expectancy should accompany this increase. , To extend the healthy life expectancy, the maintenance and recovery of oral and locomotory functions are crucial, for which dental implantation and orthopedic bone regeneration are effective. − Bone augmentation is often needed for dental implants when the alveolar bone is resorbed. − To address this issue, granular scaffolds, rather than blockish scaffolds, are often used for bone regeneration, − and they have been frequently used for the regeneration of intrabony defects formed by trauma and tumorectomy in orthopedic surgery . Although autologous bone grafting is currently the gold standard in bone regeneration, it can severely damage the donor site, thus providing a limited amount of harvested bone and delaying surgery. − To counteract these drawbacks, synthetic scaffolds for bone regeneration should be developed.…”