Impact of omphalocele size on associated conditions

Kumar, Hari R.; Jester, Andrea L.; Ladd, Alan P.

doi:10.1016/j.jpedsurg.2008.08.050

Cited by 53 publications

(50 citation statements)

References 9 publications

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“…However, using single omphalocele size criteria across gestation does not account for fetal growth [17,18]. Therefore, since 1997, despite early publications demonstrating no association of OD/AC ratio and prediction of prognosis [19], we introduced as a protocol in omphalocele evaluation the measurement of a herniated sac, description of the contents and measurement of the abdominal defect.…”

Section: Discussionmentioning

confidence: 99%

Should We Measure Fetal Omphalocele Diameter for Prediction of Perinatal Outcome?

Kiyohara

Brizot²,

Liao³

et al. 2013

Fetal Diagn Ther

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Objective: To evaluate the fetal omphalocele diameter/abdominal circumference ratio (OD/AC) as a predictor of adverse perinatal outcome. Methods: Analysis involving 47 singleton pregnancies with fetal omphalocele, normal karyotype and absence of other major abnormalities. The OD/AC ratio was determined antenatally by ultrasound and the best cutoff for the prediction of neonatal death was determined by receiver operating characteristic curve analysis. Additional secondary outcomes included need for oral intubation in the first 24 h of life, two-step surgery or use of synthetic mesh, reoperation, parenteral feeding and need for respiratory assistance >21 days, time to first oral feed, and time to hospital discharge. Results: Fetal OD/AC did not change significantly with gestational age. Postnatal death occurred in 10 (21.3%) cases and the best cutoff for prediction was an OD/AC ratio ≥0.26. In pregnancies with the first ultrasound evaluation performed before 31 weeks' gestation and an OD/AC ≥0.26, the likelihood ratio for needing intubation in the first 24 h of life was 2.6 (95% CI: 1.2-5.7), needing two-step surgery or use of mesh was 4.9 (95% CI: 1.9-14.4), and postnatal death was 4 (95% CI: 1.9-7.5). Conclusion: A fetal ultrasound OD/AC ratio ≥0.26 is associated with increased postnatal morbidity and mortality.

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Section: Discussionmentioning

confidence: 99%

Should We Measure Fetal Omphalocele Diameter for Prediction of Perinatal Outcome?

Kiyohara

Brizot²,

Liao³

et al. 2013

Fetal Diagn Ther

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“…We interrogated the literature and found 19 reports [4][5][6][7][8][9][10][11][12][13][14][15][16][17] of omphalocele associated with intestinal atresia (Table 1). In 8 cases [4,6,7,[11][12][13], the authors concluded the atresia occurred secondary to intestinal compression by a tight defect.…”

Section: Discussionmentioning

confidence: 99%

“…In 3 cases [5,14,15], the authors concluded the omphalocele and intestinal atresias occurred independently of one another. Finally, in 8 cases [8][9][10]16,17], the origins of the atresia were not commented upon. Despite the fact that …”

Section: Discussionmentioning

confidence: 99%

Mechanical compression with secondary ischemia as a possible cause of atresias associated with omphalocele

Carnaghan

Jesudason

Miniati

2009

Journal of Pediatric Surgery

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“…18 There might be an association between defect size and type of additional malformation. Kumar et al 19 found intestinal malformations frequently associated with defects <4 cm, whereas cardiac malformations were seen more often in defects >4 cm.…”

Section: Postnatal Considerationsmentioning

confidence: 98%

Giant omphalocele: current perspectives

Mack¹,

Rogdo²

2016

RRN

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Giant omphalocele (GO) is a congenital ventral abdominal wall defect characterized by a large opening with herniated abdominal organs, including liver, loss of abdominal cavity volume, and other associated congenital anomalies. Treatment of patients with GO represents a major challenge for involved caregivers. Despite significant improvements in neonatal intensive and surgical care over the last decades, the condition is still associated with high mortality rates and a high risk of severe morbidity in survivors. The principles of the earliest attempts to treat GO surgically and conservatively are still easily recognized in the main approaches used today. In this review, we discuss the more recent developments in the treatment of GO, including perioperative management and associated morbidities of the condition.

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Impact of omphalocele size on associated conditions

Cited by 53 publications

References 9 publications

Should We Measure Fetal Omphalocele Diameter for Prediction of Perinatal Outcome?

Should We Measure Fetal Omphalocele Diameter for Prediction of Perinatal Outcome?

Mechanical compression with secondary ischemia as a possible cause of atresias associated with omphalocele

Giant omphalocele: current perspectives

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