Inefficient use of personal protective equipment (PPE) is generally seen by many construction industries around the world as a catalyst for increasing accidents, diseases, illness and fatalities at workplaces. The study investigates on the factors inhibiting efficient use of PPE among construction workers at Arusha urban. Data used in this study was derived from both primary and secondary sources. Secondary data was collected from a detailed review of relevant literature to the theme investigated. Primary data was collected through a structured questionnaire aimed at 60 respondents (engineers, technicians and artisans) who have knowledge and experience of construction activities. And 42 questionnaire forms were received constituting 70 per cent response rate which was considered adequate for data analysis. The rated variables were ranked with regard to their importance and occurrence. Findings revealed that business as usual and violations of work ethics were issues of concern related to factors of inefficient use of PPE. The critical factors included lack of awareness on OHS issues, inappropriate use of PPE and negligence to provide PPE respectively. It was also found that poor supervision on the use of PPE could be significant factor inhibiting efficient use of PPE. Though thermal discomfort was ranked the lowest with regard to inefficient use of PPE, it could be significant to some parts of the country with high temperature. The study suggests that there should be routine revision of OHS governing rules to respond to emerging challenges related to health and safety in the construction industry.