“… 34 Recent evidence in humans indicates mild to moderate sleep apnea is common among patients with coronary artery diseases with increased LV wall thickness. 35 , 36 , 37 In addition, sleep restriction in the MI rat model leads to an enlarged heart size and concomitantly progresses to HF. 38 In line with these studies, we observed enlarged hearts with increased expression of HF markers, such as Nppa and Nppb , in Tg-SF mouse hearts compared to Tg-NSF mouse hearts.…”