Impact of Obesity on Clinical Outcomes in Urban Children Hospitalized for Status Asthmaticus

Aragona, Elena; El-Magbri, Eussra; Wang, Justin; Scheckelhoff, Tessa; Scheckelhoff, Trevor; Hyacinthe, Assata; Nair, Suja J.; Khan, Amina; Niño, Gustavo; Pillai, Dinesh K.

doi:10.1542/hpeds.2015-0094

Cited by 35 publications

(32 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The prevalence of overweight and obesity in this sample (32.9%) is similar to the prevalence of overweight and obesity in the general population at the time of the study (31.8%). 50 This study, as in a recent study by Aragona et al, 36 did not find a significant relationship between overweight or obesity and inpatient asthma clinical outcomes. It should be considered that LOS and admission to the ICU may be insensitive measures of the severity of the episode.…”

Section: Discussionsupporting

confidence: 66%

Lack of Recognition, Diagnosis, and Treatment of Overweight/Obesity in Children Hospitalized for Asthma

Borgmeyer

Ercole²,

Niesen

et al. 2016

Hospital Pediatrics

View full text Add to dashboard Cite

A B S T R A C TOBJECTIVES: Information is lacking regarding recognition and treatment of overweight and obesity in children hospitalized for asthma. The study objectives were to determine the current practice of recognition, diagnosis, and treatment of overweight and obesity for children hospitalized for asthma and to describe demographic, asthma, and weight characteristics for these patients. METHODS:A retrospective record review was conducted for children admitted to the hospital with asthma in 2012. Charts were reviewed for evidence of recognition, diagnosis, and treatment of overweight and obesity. Subjects were classified into age-adjusted Centers for Disease Control and Prevention weight categories based on BMI percentile and chronic asthma severity categories according to National Asthma Education and Prevention Program guidelines. RESULTS:A total of 510 subjects aged 3 to 17 years were studied. Obesity was present in 19.6% and overweight in 13.3% of subjects. BMI percentile was recorded in only 3.3% of all charts, in only 11% of subjects with obesity, and in 0% of subjects with overweight. BMI percentile was documented more often in subjects with severe obesity (P 5 .013) and with moderate to severe persistent asthma (P 5 .035). Only 9 of 168 subjects who were overweight or obese (5.6%) were given a discharge diagnosis indicating overweight or obesity, and 14 (8.3%) received treatment. Chronic asthma severity differed by BMI weight category (P , .001), with a significant relationship between obesity status and chronic asthma severity in older subjects (P 5 .033). There were no differences in severity of acute episodes based on weight group.CONCLUSIONS: Overweight and obesity were underrecognized, underdiagnosed, and undertreated in children hospitalized for asthma.

show abstract

Section: Discussionsupporting

confidence: 66%

Lack of Recognition, Diagnosis, and Treatment of Overweight/Obesity in Children Hospitalized for Asthma

Borgmeyer

Ercole²,

Niesen

et al. 2016

Hospital Pediatrics

View full text Add to dashboard Cite

show abstract

“…Aragona et al 9 retrospectively enrolled a total of 333 children between ages of 2-18 years according to specific criteria to determine the effect of obesity on outcomes among urban children hospitalized with status asthmaticus. They found that overweight/obese status was associated with subsequent emergency department visits especially in preschool-age children (<5years) were 2.3 times more likely to have a subsequent emergency department visit than lean peer.…”

Section: Resultsmentioning

confidence: 99%

“…Also, unintentionally the authors found during reviewing the medical records that asthma severity was higher in children with gestational age <32 week. Aragona et al 9 finalized that interventions to decrease obesity can improve asthma outcome.…”

Section: Resultsmentioning

confidence: 99%

“…They found that the delay of intervention is because ER doctors sometimes do not reach to the correct diagnosis and use the correct management 8 . Aragona et al 9 focused on the obesity and its role in asthma as a significant risk factor especially in preschool children 9 . The results showed that obese children visit ED because of asthma more often than the control group, which were lean patients and they also, have higher percentage of ICU admissions resulting from asthma.…”

Section: Discussionmentioning

confidence: 99%

“…We advise to conduct a research regarding this issue and see if more sibling means more sources of chest infections and triggers. Aragona et al 9 found that asthma severity was higher in children with gestational age <32 weeks. This finding needs further case control and cohort studies to assess the relation between gestational age and occurrence of asthma, and evaluate the procedures that can be done in order to provide a better management plan for preterm infants.…”

Section: For Future Perspectivementioning

confidence: 97%

See 2 more Smart Citations

Evaluation of the Risk Factors and Emergency Management Plan of Status Asthmatics in Children: A Simple Literature Review

Alshuraym

Albahouth

2018

The Egyptian Journal of Hospital Medicine

View full text Add to dashboard Cite

Background: Significant research papers were published to assess different risk factors associated with development of status asthmaticus (SA) in children and prevention. Understanding the different risk factors associated with SA development in children will help in the early prediction of the cases that might develop SA in future which may cause death in few cases. Objectives: In this study, we aimed at evaluating the various risk factors, etiologies that stand behind of status asthmaticus development and Assessment of SA management in emergency department. Methods: PubMed database were used for articles selection. All relevant articles related to our review were chosen to cover the following topics: Asthma, SA management, SA in children risk factors. We excluded other articles, which are not related tour objectives . The data have been extracted according to specific form to be reviewed by the group members to assess the different risk factors, and management modalities of SA. Conclusion: Delay in seeking medical help, poor compliance to the treatment, multiple previous admissions, frequent chest infections, and obesity are major risk factors of complicating asthma in children leading to life threatening attacks (SA). Preventing the risk factors is major task of the management and it is as important as the treatment of asthmatic attacks.

show abstract

Dietary choline intake and its association with asthma: A study based on the National Health and Nutrition Examination Survey database

Shi,

Lin,

Jiang

et al. 2024

Clinical & Translational All

View full text Add to dashboard Cite

ObjectiveThis work endeavored to examine the correlation between dietary choline intake and the odds of asthma, utilizing data from the National Health and Nutrition Examination Survey (NHANES).MethodsAggregated data from seven cycles (2005–2018) in the NHANES database were utilized. The independent variable was dietary choline intake, and the dependent variable was asthma. The weighted logistic regression method was used to construct a model reflecting the relationship between these two factors. This work employed stratified analysis without adjusting for confounding factors and subgroup analysis with adjusted confounding factors to mine the association between dietary choline intake and asthma. Additionally, restricted cubic spline analysis examined nonlinear associations of the two in age subgroups.ResultsForty five thousand and seven hundreds ninety seven samples were included here. The model indicating the relationship between dietary choline intake and asthma was constructed (OR: 0.86, 95% CI: 0.79–0.93, p < 0.001). Stratified analysis indicated that the interaction terms of age (p < 0.001) and body mass index (BMI) (p = 0.002) with dietary choline intake significantly influenced the relationship model. In the adjusted models, accounting for demographic characteristics, poverty impact ratio, BMI, exposure to environmental tobacco smoke, and total energy intake, an increase in dietary choline intake significantly reduced the odds of asthma (OR: 0.79, 95% CI: 0.72–0.88, p < 0.001). Subgroup analyses based on age and BMI revealed a significant negative correlation between dietary choline intake and the odds of asthma in the adult population (OR: 0.76, 95% CI: 0.67–0.86, p < 0.001), as well as in individuals with a BMI between 25 and 30 kg/m2 (OR: 0.79, 95% CI: 0.63–0.99, p = 0.042), and those with a BMI >30 kg/m2 (OR: 0.73, 95% CI: 0.60–0.89, p = 0.002).ConclusionDietary choline intake was significantly inversely correlated with asthma prevalence, especially in adults and overweight/obese individuals, suggesting that increasing choline intake may reduce asthma risk. Further research is needed to explore this relationship and provide tailored dietary recommendations for different age and BMI groups to enhance asthma prevention and management.

show abstract

Impact of Obesity on Clinical Outcomes in Urban Children Hospitalized for Status Asthmaticus

Cited by 35 publications

References 49 publications

Lack of Recognition, Diagnosis, and Treatment of Overweight/Obesity in Children Hospitalized for Asthma

Lack of Recognition, Diagnosis, and Treatment of Overweight/Obesity in Children Hospitalized for Asthma

Evaluation of the Risk Factors and Emergency Management Plan of Status Asthmatics in Children: A Simple Literature Review

Dietary choline intake and its association with asthma: A study based on the National Health and Nutrition Examination Survey database

Contact Info

Product

Resources

About