Impact of Nutritional Factors on Incident Kidney Stone Formation: A Report From the WHI OS

Sorensen, Mathew D.; Kahn, Arnold J.; Reiner, Alex P.; Tseng, Timothy Y.; Shikany, James M.; Wallace, Robert B.; Chi, Thomas; Wactawski‐Wende, Jean; Jackson, Rebecca D.; OʼSullivan, Mary J.; Sadetsky, Natalia; Stoller, Marshall L.

doi:10.1016/j.juro.2011.12.077

Cited by 92 publications

(60 citation statements)

References 29 publications

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“…Higher incidence of stone formation was associated with lower calcium intake, according to a huge epidemiological study carried-out among healthy men (11). Similar results were obtained in the nurses health studies I and II (3,12) and in the women's health initiative (10). Such unexpected effect is due to increased levels in urinary oxalate secondary to its reduced binding to calcium in the gastrointestinal tract.…”

Section: Discussionsupporting

confidence: 57%

“…One-fifth of the participants in this study reported using calcium supplements with no significant association with those having a history of kidney stones. It is wellknown that calcium absorption through the intestine is important in renal stones development (10). The proportions of calcium absorption from dietary and supplemental sources tend to be higher among those with nephrolithiasis history (10).…”

Section: Discussionmentioning

confidence: 99%

“…It is wellknown that calcium absorption through the intestine is important in renal stones development (10). The proportions of calcium absorption from dietary and supplemental sources tend to be higher among those with nephrolithiasis history (10). However, dietary calcium restriction is no longer recommended in patients with kidney stones.…”

Section: Discussionmentioning

confidence: 99%

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Calcium and vitamin D supplements administration in patients with nephrolithiasis; an observational prospective study

Akel¹,

Fahs²

2017

J Parathyr Dis

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Introduction: Calcium and vitamin D supplements intake have been linked to nephrolithiasis as around 80% of kidney stones contain calcium. However, studies regarding these supplements administration yielded conflicting data. Objectives: In this study we aimed to assess calcium and vitamin D supplements intake and the presence of significant association with nephrolithiasis among Lebanese patients. Patients and Methods:The study was conducted at nephrology clinics selected randomly from all Lebanese districts over a 3-month period. Data analysis was conducted with SPSS version 22. Results: The mean age of the 550 studied participants was 42.12±15.59 years with 51.5% males and 48.5% females. Almost half of the participants had a history of kidney stones (53.8%). Calcium and vitamin D supplements were utilized by 19.6% and 18.2%, respectively. Calcium and vitamin D supplements intake were not associated significantly with history of kidney stones (calcium: 10.4% versus 9.3%, P = 0.446; vitamin D: 9.1% versus 9.1%, P = 0.231). Conclusion: This study revealed that supplemental calcium and vitamin D intake among nephrolithiasis patients had no significant associations with history of kidney stones. Those patients, especially those taking calcium supplements should be counseled to monitor regularly their calcium levels to avoid hypercalciuria and consequent stone formation. Keywords: Calcium, vitamin D, Supplements, Nephrolithiasis, Kidney, Stones Please cite this paper as: Akel MG, Fahs IM. Calcium and vitamin D supplements administration in patients with nephrolithiasis; an observational prospective study. J Parathyr Dis. 2018;6(2):39-41.

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Section: Discussionsupporting

confidence: 57%

Section: Discussionmentioning

confidence: 99%

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Calcium and vitamin D supplements administration in patients with nephrolithiasis; an observational prospective study

Akel¹,

Fahs²

2017

J Parathyr Dis

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“…[31][32][33][34][35] In a meta-analysis of randomized controlled trials (RCTs) and observational studies on fluid intake, the risk reduction was in the range of 60-80%. 36 Low urine volume was found to be a significant risk factor for recurrent stone disease in patients with idiopathic calcium stones and large fluid intake is suggested as the initial therapy for prevention of stone recurrences.…”

Section: Fluid Intakementioning

confidence: 99%

“…50 Higher calcium intake decreased the risk of stones in women by up to 28% in a prospective cohort study. 31 In a large prospective cohort of women, dietary calcium was compared to supplemental calcium. The women in the highest quintile of dietary calcium had significantly lower risk; however, risk was slightly increased in women who took supplemental calcium.…”

Section: Calciummentioning

confidence: 99%

CUA guideline on the evaluation and medical management of the kidney stone patient ‒ 2016 update

Dion¹,

Ankawi²,

Chew³

et al. 2016

CUAJ

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Prevalence of urolithiasis in Sarawak and associated risk factors: An ultrasonagraphy‐based cross‐sectional study

et al. 2022

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Objective The aim of this research is to study the prevalence of urolithiasis among the population of Sarawak Malaysia and the associated risk factors. Patients and Methods A survey was conducted among individuals aged ≥18 years age in three primary health care clinics in the main cities of Sarawak from March 2019 to March 2020. Participants underwent face‐to‐face interview using a predesigned and standardised questionnaire. Details on demographic data, comorbidities, dietary variables and lifestyle were collected. Ultrasonographic examination of the kidney, ureter and bladder was performed followed by blood and urine sampling. Prevalence was defined as the proportion of participants with kidney stones, and univariate logistic regression was used to estimate the associated factors. Results A total of 1087 participants (486 male, 601 female) completed the questionnaire. Ultrasonographic examination and laboratory investigation were carried out, with an overall response rate of 98.8%. The prevalence of ultrasonographic proven urolithiasis in the sample studied was 4.04%. The mean age of patients with urolithiasis was 50.05 (SD 14.6, range 18–89), and the male to female ratio was 1.2: 1. Univariate analysis showed that odd ratio of personal history of urolithiasis (0.16, p:0.00), salty food intake (0.39, p:0.02), family history of urolithiasis (0.39, p:0.01), and hypertension (1.77, p:0.04) was significantly associated with a greater risk of urolithiasis. Conclusion The prevalence of urolithiasis in this study population is 4.04%. It affects males and females equally; 61.4% are in the age group of 25–64 years. Hypertension, high salt diet, personal history of urolithiasis and family history of urolithiasis are significant risk factors.

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Impact of Nutritional Factors on Incident Kidney Stone Formation: A Report From the WHI OS

Cited by 92 publications

References 29 publications

Calcium and vitamin D supplements administration in patients with nephrolithiasis; an observational prospective study

Calcium and vitamin D supplements administration in patients with nephrolithiasis; an observational prospective study

CUA guideline on the evaluation and medical management of the kidney stone patient ‒ 2016 update

Prevalence of urolithiasis in Sarawak and associated risk factors: An ultrasonagraphy‐based cross‐sectional study

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