Impact of nutritional assessment on long‐term outcomes in patients with carotid artery stenting

Abstract

Stroke is a leading cause of disability and death worldwide.Atherosclerotic narrowing of the extracranial carotid arteries is responsible for approximately one-fifth of all strokes. 1 There are two main interventional treatment methods in symptomatic or asymptomatic high-grade carotid artery stenosis: carotid artery stenting (CAS) and carotid endarterectomy. 2,3 Although there is sufficient evidence on the long-term outcomes of patients after CAS, potential risk factors affecting the long-term course of the disease have not yet been studied sufficiently. 4,5 Comorbid diseases accompanying severe CAS affect the long-term outcomes of the disease. Although risk factors showing long-term consequences such as diffuse proliferative hyperplasia after CAS, low highdensity lipoprotein cholesterol level, diabetes mellitus (DM), low body mass index (BMI), and contralateral carotid artery occlusion have so far been identified, a detailed risk assessment has not yet been performed. [6][7][8][9][10] Malnutrition is associated with adverse outcomes in many diseases. 11,12 The Controlling Nutritional Status (CONUT) score is an objective index widely used for evaluating nutritional status of individuals. The CONUT score is calculated based on serum albumin level, total cholesterol level, and total lymphocyte count and it can assess

Baseline Objective Malnutritional Indices as Immune-Nutritional Predictors of Long-Term Recurrence in Patients with Acute Ischemic Stroke

“…Therefore, when the PNI score was treated as a binary variable (low PNI score (≤44.75) and high PNI score (>44.75)), it was more predictive than its standard scoring system (absent, moderate, and severe) in the AIS population. Our finding was comparable with the study that investigated the long-term prospective implications of malnutrition in carotid artery stenting (CAS) patients, where results have indicated that at a cutoff value of 1.5 and 46, respectively, the CONUT and PNI score predicted long-term all-cause death and stroke with moderate sensitivity and a specificity [ 26 ].…”

The long-term prognostic value of serum 25(OH)D, albumin, and LL-37 levels in acute respiratory diseases among older adults

“…Albumin is the most abundant plasmatic protein and its widely used as indicator of malnutrition [ 17 ]. Malnutrition again is associated with poor clinical outcome in many diseases such as cardiovascular disease [ 18 , 19 ]. Hypoalbuminemia is prognostic factor for mortality among older adults [ 17 , 20 ].…”