Impact of nonlinear heat transfer on temperature control in regional hyperthermia

Lang, Jens; Erdmann, Bodo; Seebass, M.

doi:10.1109/10.784145

Cited by 192 publications

(166 citation statements)

References 14 publications

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“…Moreover, T a is the basal body temperature (at 37°C), w b is the mass flow rate which depends on tissue and temperature, c b is the blood specific heat [21]. Given the magnetic field H obtained after solving the magnetic problem, the power density source, P, due to the NPs concentration, φ, is computed as follows [2]:…”

Section: Thermal Problemmentioning

confidence: 99%

Field synthesis for the optimal treatment planning in Magnetic Fluid Hyperthermia

Barba¹,

Dughiero²,

Sieni³

2012

Archives of Electrical Engineering

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Section: Thermal Problemmentioning

confidence: 99%

Field synthesis for the optimal treatment planning in Magnetic Fluid Hyperthermia

Barba¹,

Dughiero²,

Sieni³

2012

Archives of Electrical Engineering

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“…The port-a-cath was assumed to be made of silicone or titanium, which was simulated as a lossy metal using the surface impedance boundary condition (SIBC) in SEMCAD-X. Table 1 shows the dielectric and thermal properties of tissues used in EM and thermal simulations [11,12]. Where "r is the relative permittivity; s (S/m) the electrical conductivity, (kg/m 3 ) the tissue density, c (J/kg K) the specific heat capacity, k (W/m K) the thermal conductivity, o (mL/min kg) is the blood perfusion and Q (W/ kg) is the heat generation rate.…”

Section: Electromagnetic Modelsmentioning

confidence: 99%

“…Table 1. Dielectric and thermal tissues properties used for the models at 433 MHz [11,12]. direction of every LCA is rotated 90 degrees for each consequent treatment [1,13].…”

Section: Electromagnetic Modelsmentioning

confidence: 99%

Impact of silicone and metal port-a-cath implants on superficial hyperthermia treatment quality

Trujillo-Romero

Paulides

Drizdal

et al. 2014

International Journal of Hyperthermia

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Purpose: A port-a-cath is a device implanted under the skin for continuous drug administration. It is composed of a catheter and a silicone or metal reservoir. A simulation study was done to assess the impact of a port-a-cath implant on the quality of superficial hyperthermia treatments applied using the Lucite cone applicator (LCA). Methods: Specific absorption rate (SAR) and temperature distributions were predicted using SEMCAD-X (version 14.8). We simulated 72 arrangements: two LCA-implant set-ups (central port-a-cath or at an edge below the LCA footprint), six translations of the LCA per set-up, two LCA orientations (Parallel or perpendicular electric field direction) per set-up, two implant materials (silicon or metal) and a control without port-a-cath. Treatment quality was quantified by the average 1 g SAR coverage (CV 25% ), i.e. volume within the 25% iso-SAR surface, and the volume within the 40 C iso-temperature surface (CV 40 C ). Results: CV 25% reduced with a silicon port-a-cath located below the LCA footprint. In the worst scenario, only 64% of the CV 25% of the control set-up was achieved. For a metal port-a-cath below the LCA aperture, dramatic reductions of CV 25% were predicted: worst scenario down to 12.1% of the control CV 25% . For the CV 40 C the worst case values were 74.5% and 6.5%, for silicon and metal implants, respectively. Conclusions: A silicone port-a-cath below the LCA had a smaller effect on treatment quality than a metal implant. Based on this study we recommend verifying heating quality by 3D patient-specific treatment planning when a port-a-cath is located below the footprint of the applicator.

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“…Lang et al 154 described an optimization process specially designed for regional hyperthermia of deep-seated tumors in order to achieve desired steady-state temperature distributions. A nonlinear threedimensional heat transfer model based on temperature-dependent blood perfusion was applied to predict the temperature.…”

Section: Iiif Applications Of Bioheat Transfer Modelsmentioning

confidence: 99%

Thermal Therapy, Part IV: Electromagnetic and Thermal Dosimetry

Habash

Bansal

Krewski

et al. 2007

Crit Rev Biomed Eng

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ABSTRACT:In this article some of the important techniques in electromagnetic (EM) and thermal dosimetry are reviewed. Three major areas are discussed: modeling power deposition and estimation of EM energy absorbed by tissues exposed to EM radiation, electrical-thermal modeling for thermal therapy with various models of heat transfer in living tissues, and thermal dosimetry using invasive and noninvasive thermometry. Knowledge about the temperature distributions achieved can only be obtained by treatment planning of patient therapy. This process is called thermal therapy planning system (TTPS), which is a large and complex system for design, control, documentation, and evaluation of the treatment that also provides data for treatment optimization. Various imaging techniques for guidance and monitoring necessary for clinical treatments are also discussed. The review concludes by suggesting future avenues for investigations.

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Impact of nonlinear heat transfer on temperature control in regional hyperthermia

Cited by 192 publications

References 14 publications

Field synthesis for the optimal treatment planning in Magnetic Fluid Hyperthermia

Field synthesis for the optimal treatment planning in Magnetic Fluid Hyperthermia

Impact of silicone and metal port-a-cath implants on superficial hyperthermia treatment quality

Thermal Therapy, Part IV: Electromagnetic and Thermal Dosimetry

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