Impact of microvessel density on lymph node metastasis and survival after curative resection of pancreatic cancer

Abstract

This study confirms the role of angiogenesis in PC and identifies MVD as an independent prognostic factor in patients with curatively resected PC.

Endoglin (CD105) expression on microvessel endothelial cells in juvenile nasopharyngeal angiofibroma: Tissue microarray analysis and association with prognostic significance

“…higher than those of patients with lower MVD. This result is consistent with previous studies of other solid tumors 17,26. Furthermore, MVD was not associated with any clinicopathologic features, such as age, JNA operation history, operation approach, tumor stage, or hemorrhage during the operation.…”

Zerumbone Inhibits Angiogenesis by Blocking NF-κB Activity in Pancreatic Cancer

“…42,43 In addition, our results of angiogenesis assay may indicate that BxPC-3 increased the abnormal HUVEC tube formation and network (Fig. 42,43 In addition, our results of angiogenesis assay may indicate that BxPC-3 increased the abnormal HUVEC tube formation and network (Fig.…”

Pancreatic stellate cells regulate blood vessel density in the stroma of pancreatic ductal adenocarcinoma

“…TMAs were stained with CD31 antibody (Rabbit anti Human ab28364 Abcam, Cambridge, MA) for the presence of vascular structures. Micro Vascular Density (MVD = number of vessels/mm 2 ) and Total Vascular Area (TVA = area occupied by vascular structures as proportion of the total area expressed in/1000 or ‰) were considered as indices of vascularisation [11], [12], [13]. The Ariol™ imaging analysis system (Genetix, New Milton, England) was used to determine vascular indices.…”