Impact of Medication Nonadherence on Hospitalizations and Mortality in Heart Failure

Fitzgerald, Ashley A.; Powers, J. David; Ho, P. Michael; Maddox, Thomas M.; Peterson, Pamela N.; Allen, Larry A.; Masoudi, Frederick A.; Magid, David J.; Havranek, Edward P.

doi:10.1016/j.cardfail.2011.04.011

Cited by 233 publications

(177 citation statements)

References 32 publications

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“…11 In another study, patients who did not adhere to their prescribed medication regimen were two times as likely to be admitted to hospital and three times as likely to experience death compared to patients who were adherent to their regimens. 12 Moreover, when patients are non-adherent to their drug therapy, symptoms are less likely to be controlled. 10 These studies indicate the importance of following prescribed medication regimens to decrease adverse events in heart failure.…”

Section: Challenges Of Medication Adherencementioning

confidence: 99%

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Improving medication adherence of patients with chronic heart failure: challenges and solutions

Shah¹,

Simms²,

Barksdale³

et al. 2015

RRCC

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Heart failure is a chronic debilitating illness that affects 5.7 million Americans. The financial burden of heart failure in the US toppled $31 billion in 2012, which is one of the highest among all chronic medical conditions. Medication adherence is a major component of heart failure self-care behaviors. Therefore, medication non-adherence is associated with more emergency department visits, frequent rehospitalizations, and higher medical cost. Medication adherence rates have varied from 10% to 98% depending on the definition and measurement used to assess and analyze adherence. Many factors contribute to medication non-adherence such as lack of support, finances, absent of symptoms, cognitive decline, adverse reactions, depression, poor attention span, poor knowledge about medication, multiple medications, difficulty swallowing large pills, and inconveniences of urinary frequency with diuretics. Researchers have explored various strategies such as the use of pharmacists, nurses, telemedicine, and interdisciplinary teams to provide interventions to improve medication adherence in heart failure. Health care providers should continue to provide education, constantly reinforce the importance of taking medication as prescribed, and when feasible, utilize one of the successful evidence-based strategies to increase adherence.

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Section: Challenges Of Medication Adherencementioning

confidence: 99%

“…10 These studies indicate the importance of following prescribed medication regimens to decrease adverse events in heart failure. [10][11][12] In the following section, we discuss challenges and factors that affect adherence to medication.…”

Section: Challenges Of Medication Adherencementioning

confidence: 99%

Improving medication adherence of patients with chronic heart failure: challenges and solutions

Shah¹,

Simms²,

Barksdale³

et al. 2015

RRCC

View full text Add to dashboard Cite

show abstract

“…Let's look at one such example from the NT, bearing in mind that compliance is an important factor in clinical outcomes [43]. A 50 year Indigenous male with CHF, stage 3 renal impairment and several other metabolic comorbidities.…”

Section: What Is the Level Of Evidence For Hf Therapies In The Nt Conmentioning

confidence: 99%

Do We Need A Wider Therapeutic Paradigm For Heart Failure With Comorbidities?: A Remote Australian Perspective

Iyngkaran¹,

Thomas²

2016

Health Care: Current Reviews

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Forty percent of CHF clients can suffer with up to five or more comorbidity, a rate that is likely higher in the NT. Large CHF trials AbstractCongestive Heart Failure a leading cause of morbidity and mortality is often associated with comorbidities and with it polypharmacy. Improved pathophysiological understanding, the available therapeutics, clinical guidelines and structured programs for comprehensive care have not benefited all clients in the Northern Territory of Australia. The Northern Territory has both a unique geography and demography including a sizeable Indigenous population. Additional factors that can affect heart failure management are prevalent in remote areas and are not well addressed within randomized controlled trials. This review is focused on building a case for widening the therapeutic paradigm for heart failure with comorbidities. We focus on a brief overview of heart failure and its associated comorbidities, the common overlapping physiological processes, the interpretation of the external validity of trial evidence, and finally exploring the available evidence for the important therapies within the guidelines. A need to consider a wider therapeutic paradigm may also have relevance for clients in other health systems.

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“…However patients' non-adherence, in medication and in general in the provided by the experts' guidance, is "epidemic" [19]. This non-adherence behavior is a barrier to taking advantage of the existing knowledge and progress in medicine and has a negative impact in the patient's clinical condition, and consequently in his/her autonomy, physical and mental health and in general in QoL.…”

Section: B Description Of the Conditionmentioning

confidence: 99%

The Evolution of mHealth Interventions in Heart Failure

Karanasiou¹,

Tripoliti²,

Kalatzis³

et al. 2016

XIV Mediterranean Conference on Medical and Biological Engineering and Computing 2016

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Abstract-Heart Failure (HF) is among the most deadly diseases globally with reduced quality of life (QoL), repeatable hospitalizations, and early mortality. For effectively managing HF patients should systematically monitor their symptoms and follow the experts' guidelines. While the precise mechanism behind HF disease has not been fully delineated, risk factors for HF have been identified. Though the risk factors are known, these is a compelling need for efficient and effective management and monitoring the progress of HF. Mobile health (mHealth) intervention has the potential to offer personalized services for predictive, participatory and preventative care and contribute to more accessible, faster and reliable disease monitoring. In this work we present an extended review of the evolution of mHealth interventions in cardiology and HF and the emerging potential these resources provide.

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Impact of Medication Nonadherence on Hospitalizations and Mortality in Heart Failure

Cited by 233 publications

References 32 publications

Improving medication adherence of patients with chronic heart failure: challenges and solutions

Improving medication adherence of patients with chronic heart failure: challenges and solutions

Do We Need A Wider Therapeutic Paradigm For Heart Failure With Comorbidities?: A Remote Australian Perspective

The Evolution of mHealth Interventions in Heart Failure

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