Impact of medication characteristics and adverse drug events on hospital admission after an emergency department visit: Prospective cohort study

Abstract

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Frequency, Characteristics, and Predictive Factors of Adverse Drug Events in an Adult Emergency Department according to Age: A Cross-Sectional Study

“…Details of the intervention have been published elsewhere [ 27 , 28 ]. Briefly, a member of the pharmaceutical team, which is part of the general ED staff, conducted an interview with each patient to obtain the medication history and then begin the ADE detection process.…”

“…This definition includes signs, symptoms, and laboratory abnormalities resulting from adverse drug reactions (ADRs) or noncompliance with medication prescriptions. The method for identifying and validating an ADE has been described elsewhere [ 27 , 28 ] and is summarized in Supplementary Figure S1 . A pharmacist and an ED physician independently identified the ADEs and consulted an expert committee in cases of doubt about the diagnosis or category.…”

Involvement of Pharmacists in the Emergency Department to Correct Errors in the Medication History and the Impact on Adverse Drug Event Detection

“…This study is ancillary to a study on ADE detection in EDs (ADEsED). This prospective observational monocentric study was conducted in the adult ED of a university hospital in France, from November 2011 to November 2018, and the primary objective was to assess the rate and characteristics of ADEs identified by the pharmacist team in an ED [34][35][36]. Participation in the study was proposed by clinical pharmacists for all adult patients (>18 years) admitted to the ED during the study period.…”

“…Our process of medication reconciliation [37] and ADE detection has been previously published [34,35], and is briefly described below. The process is conducted by a clinical pharmacy team that includes one senior pharmacist, one pharmacist resident and four pharmacy students.…”

“…In the case of doubt about the diagnosis or the category of an ADE during the study, the case was reviewed by the expert committee. At the end of the study, ADE cases were verified by two expert clinical pharmacists and/or the expert committee, if necessary (Figure 1) [35].…”