Impact of maternal age on the incidence of obstetrical complications in Japan

Matsuda, Yoshihisa; Kawamichi, Yayoi; Hayashi, Kyozo; Shiozaki, Arihiro; Shoji, Shuichi; Saito, Shigeru

doi:10.1111/j.1447-0756.2011.01552.x

Cited by 40 publications

(38 citation statements)

References 28 publications

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“…The odds decrease as the age of woman increases. The dose-response effect that age has on the odds for infection of chorioamnionitis and endometritis during labor and delivery (Cochran-Armitage trend tests p<.001) supports past studies 11,37–39 and is of high clinical relevance. Bacteria from intrauterine infections during pregnancy can harm the fetus through systemic inflammation (a fetal inflammatory response syndrome) 40,41 and cause damage to multiple organs.…”

Section: Commentsupporting

confidence: 79%

Maternal Age and Risk of Labor and Delivery Complications

Cavazos‐Rehg

Krauss

Spitznagel

et al. 2014

Matern Child Health J

244

168

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Objective We utilized an updated nationally representative database to examine associations between maternal age and prevalence of maternal morbidity during complications of labor and delivery. Study design We used hospital inpatient billing data from the 2009 United States Nationwide Inpatient Sample (NIS), part of the Healthcare Cost and Utilization Project (HCUP). To determine whether the likelihood that maternal morbidity during complications of labor and delivery differed among age groups, separate logistic regression models were run for each complication. Age was the main independent variable of interest. Results In analyses that controlled for demographics and clinical confounders, we found that complications with the highest odds among women, 11–18 years of age, compared to 25–29 year old women, included preterm delivery, chorioamnionitis, endometritis, and mild preeclampsia. Pregnant women who were 15–19 years old had greater odds for severe preeclampsia, eclampsia, postpartum hemorrhage, poor fetal growth, and fetal distress. Pregnant women who were ≥35 years old had greater odds for preterm delivery, hypertension, superimposed preeclampsia, severe preeclampsia, and decreased risk for chorioamnionitis. Older women (≥40 years old) had increased odds for mild preeclampsia, fetal distress, and poor fetal growth. Conclusions Our findings underscore the need for pregnant women to be aware of the risks associated with extremes of age so that they can watch for signs and symptoms of such complications.

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Section: Commentsupporting

confidence: 79%

Maternal Age and Risk of Labor and Delivery Complications

Cavazos‐Rehg

Krauss

Spitznagel

et al. 2014

Matern Child Health J

244

168

View full text Add to dashboard Cite

show abstract

“…The main concern is a disparity in prevalence of coexisting diseases. The rates of chronic diseases were: thyroid disease, 12/547 (2.2%); chronic hypertension, 10/547 (1.8%); diabetes, 8/547 (1.5%); and renal disease, 4/547 (0.7%) in study participants, while those rates in the Japanese pregnant population are reported as: thyroid disease, 1.5%; chronic hypertension, 0.6%; diabetes, 2.1%; and renal disease, 1.1% . Although it appears that these small differences did not impact our main findings, caution should be exercised in generalizing our results.…”

Section: Discussionmentioning

confidence: 62%

Incidence and risk factors for recurrent spontaneous preterm birth: A retrospective cohort study in Japan

Yamashita

Hayashi

Endo

et al. 2015

J of Obstet and Gynaecol

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Aim The aim of this study was to assess the incidence and risk factors for recurrent spontaneous preterm birth (PTB) in Japan. Material and Methods A retrospective cohort study was conducted at five tertiary perinatal centers in Osaka, Japan from 2008 through 2012. Perinatal data were collected from medical records of women with a singleton gestation and a previous spontaneous PTB. Exclusion criteria were first‐trimester spontaneous abortion, first antenatal visit beyond 14 weeks of gestation, and previous PTB with medical indications, placenta previa, abruptio placenta, multiple pregnancy, fetal anomaly, and antepartum fetal demise. The associations between recurrent spontaneous PTB and perinatal factors were evaluated by logistic regression analysis. Results Of 547 women with a previous spontaneous PTB, 89 (16.3%) suffered a recurrent spontaneous PTB. The risk factors for recurrence included multiple previous spontaneous PTB (adjusted odds ratio [aOR]: 2.26; 95% confidence interval [CI]: 1.19–4.30; P = 0.013), no previous term birth (aOR: 2.08; 95%CI: 1.24–3.49; P = 0.005), and interpregnancy interval < 12 months (aOR: 2.13; 95%CI: 1.17–3.85; P = 0.013). Conclusion Approximately one in six women with a previous spontaneous PTB suffered a recurrent spontaneous PTB. Multiple previous spontaneous PTB, no previous term birth, and short interpregnancy interval were independent risk factors for recurrence.

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“…This nationwide registry was established in 1974. Detailed descriptions of the database have been published previously (20). Briefly, the attending physicians at 125 tertiary centers of the Perinatal Research Network in Japan collected yearly data for each pregnant woman in an offline clinical database with a common format.…”

Section: Methodsmentioning

confidence: 99%