Impact of Malnutrition on Long-Term Mortality in Hospitalized Patients With Heart Failure

Bonilla-Palomas, Juan L.; Gámez-López, Antonio L.; Anguita‐Sánchez, Manuel; Castillo-Domínguez, Juan C.; García-Fuertes, Daniel; Crespín-Crespín, Manuel; López‐Granados, Amador; Lezo, José Suárez de

doi:10.1016/j.rec.2011.03.008

Cited by 68 publications

(75 citation statements)

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“…The prevalence of malnutrition and frailty in our cohort was around 45% and 50% respectively, similar to findings from other studies (34% to 70% 6, 26,27 for malnutrition and 30% to 50% 28 for frailty). Ours is the first paper to compare directly several different indices of malnutrition and frailty in patients hospitalised with HF.…”

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confidence: 91%

Prognostic value of simple frailty and malnutrition screening tools in patients with acute heart failure due to left ventricular systolic dysfunction

et al. 2017

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Section: Discussionsupporting

confidence: 91%

Prognostic value of simple frailty and malnutrition screening tools in patients with acute heart failure due to left ventricular systolic dysfunction

et al. 2017

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“…Thus, it is thought that MNA ® can evaluate nutritional status even in acute HF. In the present study, many subjects were found to be in a state of malnutrition or at risk of malnutrition according to the MNA ® on admission; this finding was similar to those of Bonilla-Palomas, et al 5) in hospitalized HF patients before discharge. These results indicate that MNA ® is a useful nutritional marker, even in patients with ADHF, and that detecting the patients with malnutrition or at risk of malnutrition at the time of admission is important for planning nutritional management interventions for these patients.…”

Section: Discussionsupporting

confidence: 90%

“…Many patients with chronic HF have a poor nutritional status, which is associated with a poor prognosis, [3][4][5] similarly such as insufficient left ventricular ejection fraction (LVEF), medication, rehabilitation, 6) and self-care. 7,8) Malnutrition in HF patients causes body fluid accumulation and infection and exacerbates their general physical condition, resulting in a further deterioration in their nutritional status.…”

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confidence: 99%

“…Many studies have reported their usefulness in predicting the prognosis in patients with HF. 4,5,15,20,21) Bonilla, et al 5) assessed patients with chronic HF according to the MNA ® and found that 12.8% of patients were malnourished and 60.2% of patients were at risk of malnutrition, while only 27.0% had normal nutritional status. "At risk of malnutrition" includes the possibility of malnutrition that is necessary to be extracted.…”

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confidence: 99%

“…Lower TTR can be observed in HF patients with malnutrition determined using the MNA ® . 5) We focused on this point, and…”

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Assessment of Transthyretin Combined With Mini Nutritional Assessment on Admission Provides Useful Prognostic Information in Patients With Acute Decompensated Heart Failure

et al. 2015

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SummaryDecreased Transthyretin (TTR) can be observed in heart failure patients with malnutrition evaluated by the Mini Nutritional Assessment (MNA). This study investigated whether a combination of different nutritional assessment methods would be useful for assessing prognosis in patients with acute decompensated heart failure (ADHF).This prospective study included 52 patients with ADHF (mean age, 71.1 ± 14.7 years; men 55.8%) who were admitted to our hospital between June 2012 and August 2013. On admission, nutritional status was evaluated according to levels of TTR and the MNA. Of 52 patients, 28 (53.8%) had TTR < 15 mg/dL, 39 (75.0%) had malnutrition or were at risk of malnutrition (MNA score ≤ 23.5), and 21 (40.4%) were categorized into group L (MNA score ≤ 23.5 and TTR < 15 mg/dL). Readmission due to worsening heart failure occurred in 12 patients (23.1%), and there were 4 (7.7%) allcause deaths. The 1-year event-free survival rates in group L and the remaining patients (group O) were 27.7% and 85.6%, respectively (P = 0.001). Using Cox multivariate analysis, group L also had a poorer prognosis (hazard ratio 4.35, 95% confidence interval 1.26-17.74, P = 0.020).MNA revealed that 75% of patients with ADHF had malnutrition or were at risk of malnutrition. The combination of low MNA and low TTR on admission can predict the prognosis of patients with ADHF. (Int Heart J 2015; 56: 226-233)

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Prevalence and the factors associated with malnutrition risk in elderly Chinese inpatients

et al. 2021

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Background Malnutrition is an under recognized, but common issue in elderly patients. This study aimed to investigate the prevalence of poor nutritional status and identify comprehensive geriatric assessment‐based clinical factors associated with increased malnutrition risk to assessing malnutrition risk in hospitalized elderly patients in China. Methods A total of 365 elderly hospitalized patients (178 women, 76.37 ± 7.74 years) undertook a comprehensive geriatric assessment (CGA), and have their nutritional status assessed using the short‐form mini‐nutritional assessment. Results Among 365 patients, 32 (8.77%) were malnourished and 112 (30.68%) were at risk of malnutrition. A logistic regression analysis showed that age (odds ratio [OR], 1.59; 95% confidence interval [CI], 1.13‐2.23), alcohol consumption (OR, 2.04; 95% CI, 1.19‐3.48), presence or history of cancer or heart failure (OR, 3.48 and 2.86; 95% CI, 1.49‐8.13 and 1.12‐7.27), depression (OR, 2.86; 95% CI, 1.97‐4.17), body mass index (OR, 5.62; 95% CI, 3.62‐8.71), being dependent in activity of daily living (OR, 3.81; 95% CI, 2.61‐5.57), a lower score in instrumental activities of daily living (OR, 3.01; 95% CI, 2.09‐4.33), recent fall(s) (OR, 2.22; 95% CI, 1.37‐2.91), cognitive impairment (OR, 1.81; 95% CI, 1.30‐2.53), insomnia (OR, 1.49; 95% CI, 1.07‐2.06), hemoglobin and albumin level (OR, 1.72 and 2.86; 95% CI, 1.17‐2.50 and 1.53‐5.36) were independent correlates of malnutrition in older patients. Conclusion Our study demonstrated that age, alcohol consumption, chronic diseases (cancer and heart failure), depression, body mass index, function status, recent fall(s), cognitive impairment, insomnia, and low hemoglobin and albumin levels were independently associated with malnutrition in these patients. Comprehensive geriatric assessment can provide detailed information of older patients and can be a useful tool for assessing malnutrition risk‐associated factors.

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Impact of Malnutrition on Long-Term Mortality in Hospitalized Patients With Heart Failure

Cited by 68 publications

References 27 publications

Prognostic value of simple frailty and malnutrition screening tools in patients with acute heart failure due to left ventricular systolic dysfunction

Prognostic value of simple frailty and malnutrition screening tools in patients with acute heart failure due to left ventricular systolic dysfunction

Assessment of Transthyretin Combined With Mini Nutritional Assessment on Admission Provides Useful Prognostic Information in Patients With Acute Decompensated Heart Failure

Prevalence and the factors associated with malnutrition risk in elderly Chinese inpatients

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