Impact of Malaria during Pregnancy on Low Birth Weight in Sub-Saharan Africa

Guyatt, Helen; Snow, Robert W.

doi:10.1128/cmr.17.4.760-769.2004

Cited by 384 publications

(344 citation statements)

References 66 publications

Supporting

Mentioning

293

Contrasting

Unclassified

Order By: Relevance

“…Moreover, they show that morbidities characteristic of pregnancy (hypertension, preeclampsia, history of preterm, infectious diseases, premature rupture of membranes, and hemorrhages during pregnancy) are also risk factors for low birth weight 1,27 . In fact, infections during pregnancy are also considered risk factors, including asymptomatic bacteriuria 28 , bacterial vaginosis 29 , trichomoniasis 30 , malaria 31 and maternal periodontal disease 32,33 .…”

Section: Discussionmentioning

confidence: 99%

Factors associated with low birth weight in a historical series of deliveries in Campinas, Brazil

Coutinho¹,

Cecatti²,

Surita³

et al. 2009

Rev. Assoc. Med. Bras.

View full text Add to dashboard Cite

SummaryObjective. To identify the risk factors associated with low birth weight (<2500 grams). MethOds. Unmatched case-control study performed in a tertiary maternity hospital in Campinas, Brazil, involving 43,499 liveborn infants delivered in the institution between 1986 and 2004. Analysis of the database containing information on deliveries of women who gave birth to infants with low (6,477 cases) and normal (37,467) birth weight were performed. Factors associated with low birth weight were identified according to the odds ratio (OR) and 95% confidence interval (95%CI) in the bivariate analysis and according to the adjusted OR in the multivariate analysis. Sociodemographic characteristics, reproductive history, previous morbidity and factors related to current prenatal care were studied. Results. Extremes of reproductive age, poor education, low maternal weight, smoking beyond the fourth month of pregnancy, previous cesarean section, interdelivery interval ≤24 months and ≥37 months, maternal history of hypertension, cardiopathy and premature delivery, few (≤5) prenatal visits and beginning prenatal care late in pregnancy (after the 3rd month), premature rupture of membranes, increased blood pressure, infectious diseases and hemorrhages during current pregnancy were all associated with low birth weight. Maternal obesity and being a primipara were found to be protective factors. cOnclusiOn. These results confirm the findings of previous studies. The detection and prenatal management of modifiable factors, counseling, pre-conception intervention, adequate prenatal care and the implementation of primary and secondary prevention of maternal morbidity should be a target for all obstetrician as a potential source for reducing the incidence of low birth weight.

show abstract

Section: Discussionmentioning

confidence: 99%

Factors associated with low birth weight in a historical series of deliveries in Campinas, Brazil

Coutinho¹,

Cecatti²,

Surita³

et al. 2009

Rev. Assoc. Med. Bras.

View full text Add to dashboard Cite

show abstract

“…Approximately 74% of African malaria deaths occurred in children aged below 5 years (WHO, 2015b). Low birth weight associated with malaria in pregnancy may result in 100,000 infant deaths in Africa annually (Guyatt & Snow, 2004). In areas of high and moderate transmission, P. falciparum infection in pregnant women often occurs without symptoms but accounts for a substantial proportion of cases of maternal anaemia, low birth weight and infant deaths (Desai et al , 2007).…”

Section: Policies Regarding Antifolate Drugs Against Malariamentioning

confidence: 99%

Safety and benefits of interventions to increase folate status in malaria‐endemic areas

et al. 2017

View full text Add to dashboard Cite

SummaryFor decades, folic acid has routinely been given to prevent or treat anaemia in children, pregnant women and people with sickle cell disease. However, there is no conclusive evidence that folate deficiency anaemia constitutes a public health problem in any of these groups. Industrial flour fortification is recommended and implemented in many countries to combat neural tube defects. Dietary folates or folic acid can antagonise the action of antifolate drugs that play a critical role in the prevention and treatment of malaria. Randomised trials have shown that folic acid supplementation increases the rate of treatment failures with sulfadoxine‐pyrimethamine. The efficacy of antifolate drugs against Plasmodium is maximized in the absence of exogenous folic acid, suggesting that there is no safe minimum dose of ingested folic acid. We here review the safety and benefits of interventions to increase folate status in malaria‐endemic countries. We conclude that formal cost‐benefit analyses are required.

show abstract

“…Low birth weight in newborns from mothers who had malaria during pregnancy is common; it is estimated that it causes 5% of perinatal deaths in areas with poor resources 14 . The prevalence of infection and the density of parasites reach their peak during the first half of pregnancy and progressively decrease until delivery 15 .…”

Section: Introductionmentioning

confidence: 99%

Plasmodium falciparum infection in pregnant women attending antenatal care in Luanda, Angola

Campos

Valente

Campos³

et al. 2012

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

Introduction: Malaria during pregnancy remains a serious public health problem. The aim of this study was to establish the prevalence and possible risk factors for malaria in pregnant women attending antenatal care at Augusto Ngangula Specialized General Hospital in Luanda, Angola. Methods: Pregnant women (679 total) who attended antenatal care from April to September 2008 were included in the study after signing informed consent. For each participant, the social-demographic profile and malaria and obstetric histories were investigated via a questionnaire. Diagnosis was made by optic microscopy, and hemoglobin concentration measured. The associations between age, parity, gestational age, residence, schooling, malaria during gravity, anemia and treatment with incidence of Plasmodium falciparum infection were analyzed through logistic regression. Results: During the period of study, 74 (10.9%) out of 679 women were infected by P. falciparum. The average concentration of hemoglobin was 11.1 ± 0.07g/dL, and there were significant associations between the history of malaria during pregnancy, P. falciparum infection (p<0.01) and anemia at the time of observation (p<0.001). Conclusions: Previous history of malaria during pregnancy represents a risk factor for current infection and anemia was an important complication associated with malaria, even in women who were treated with sulfadoxine-pyrimethamine during pregnancy.

show abstract

Impact of Malaria during Pregnancy on Low Birth Weight in Sub-Saharan Africa

Cited by 384 publications

References 66 publications

Factors associated with low birth weight in a historical series of deliveries in Campinas, Brazil

Factors associated with low birth weight in a historical series of deliveries in Campinas, Brazil

Safety and benefits of interventions to increase folate status in malaria‐endemic areas

Plasmodium falciparum infection in pregnant women attending antenatal care in Luanda, Angola

Contact Info

Product

Resources

About